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54752

Sigma-Aldrich

Méthyl 4-hydroxybenzoate, 4-hydroxybenzoate de méthyle

tested according to Ph. Eur.

Synonyme(s) :

Ester méthylique d’acide p-hydroxybenzoïque, NIPAGIN, Parahydroxybenzoate de méthyle

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About This Item

Formule linéaire :
HOC6H4CO2CH3
Numéro CAS:
99-76-3
Poids moléculaire :
152.15
Numéro Beilstein :
509801
Numéro CE :
202-785-7
Numéro MDL:
MFCD00002352
Code UNSPSC :
51452201
ID de substance PubChem :
329758052
Nomenclature NACRES :
NA.25

Agence

USP/NF
tested according to Ph. Eur.

Pureté

99.7%

Forme

solid

Pf

125-128 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

Clé InChI

LXCFILQKKLGQFO-UHFFFAOYSA-N

Informations sur le gène

rat ... Ar(24208)

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Application


  • Single crystal, Hirshfeld surface and theoretical analysis of methyl 4-hydroxybenzoate, a common cosmetic, drug and food preservative-Experiment versus theory.: This research provides a detailed analysis of the crystal structure of Methyl 4-hydroxybenzoate, offering insights into its stability and effectiveness as a preservative in various applications, including cosmetics and pharmaceuticals (Sharfalddin et al., 2020).

  • Photostabilization of papaverine hydrochloride solutions.: This article explores the role of Methyl 4-hydroxybenzoate in enhancing the photostability of papaverine hydrochloride solutions, crucial for maintaining the efficacy of this pharmaceutical under exposure to light (Piotrowska et al., 2010).

Pictogrammes

Environment
GHS09

Mentions de danger

H411

Conseils de prudence

P273 - P391 - P501

Classification des risques

Aquatic Chronic 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

334.4 °F

Point d'éclair (°C)

168 °C

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCL6922
BCCK9188
BCCK3578
BCCJ8350
BCCH8766

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Ismail I Hewala et al.
Talanta, 88, 623-630 (2012-01-24)
Simple methods for HPTLC peak purity assessment and identification of the HPTLC peaks were presented. The spectrodensitograms - selected at different time intervals across the elution time of the HPTLC peak - were extracted and digital algorithms for manipulating the
Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses
Kyung-Jin Min et al.
Aging cell, 7(2), 199-206 (2008-01-29)
Reduced insulin/insulin-like growth factor (IGF) signaling may be a natural way for the reduction of dietary nutrients to extend lifespan. While evidence challenging this hypothesis is accumulating with Caenorhabditis elegans, for Drosophila melanogaster it is still thought that insulin/IGF and
K Kannathasan et al.
Acta tropica, 120(1-2), 115-118 (2011-07-19)
The vector-borne diseases caused by mosquitoes are one of the major health problems in many countries especially in tropical and sub-tropical countries. The resistance of mosquitoes to synthetic chemicals and environmental toxicity created by the chemicals raised the demand for
M G Soni et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1335-1373 (2002-10-22)
Methyl paraben (CAS No. 99-76-3) is a methyl ester of p-hydroxybenzoic acid. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. Methyl paraben is readily and completely absorbed through
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