10982962001

N-Acetyl-β-D-Glucosaminidase Standard (NAG Standard)

from beef kidney

• Synonyme(s) : NAG standard
• Code UNSPSC : 12352204

Propriétés

• Source biologique: bovine kidney
• Niveau de qualité: 100
• Forme: lyophilized
• Activité spécifique: ~20 mU/mL
• Conditionnement: pkg of 5 × 3 mL (5 x 400 μg)
• Fabricant/nom de marque: Roche
• Technique(s): activity assay: suitable
• Couleur: white to light yellow
• Solubilité: water: soluble
• Application(s): life science and biopharma
• Température de stockage: 20-25°C

Description

Description générale

Standard for the determination of NAG activity in urine research samples with the aid of the Test-Combination N-acetyl-β-D-glucosaminidase.
N-Acetyl-β-D-Glucosaminidase is a high molecular weight lysosomal enzyme existing as two isofomrs, Isoenzyme-A and Isoenzyme-B. It is present in human kidney. It has high molecular weight. It is highly active in renal proximal tubular cells. It has been reported that overexpressed urine-NAG reflects the proximal tubular dysfunction of the kidney.

Application

The NAG standard is used for the determination of NAG activity in urine in life science research applications, with the aid of N-acetyl-β-D-glucosaminidase. It can be used in automatic analyzers.

Définition de l'unité

Volume Activity: The activity of the NAG standard is approximately 20 mU N-acetyl-β-D-glucosaminidase from beef kidney per ml. For exact values, see data printed on the label.

Notes préparatoires

Storage conditions (working solution): 2 to 8 °C
Stability of the standard solution
The solution is stable for at least 1 month stored at 2 to 8 °C, protected from light.

Reconstitution

Preparation of the standard solution
Dissolve contents of one bottle with 3 ml double distilled water, close bottle and wait for 5 minutes. Dissolve contents completely by gentle swirling. Avoid creating foam.

Stockage et stabilité

Keep protected from light.

Autres remarques

For life science research only. Not for use in diagnostic procedures.

Informations sur la sécurité

• Mentions de danger: H412
• Conseils de prudence: P273 - P501
• Classification des risques: Aquatic Chronic 3
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash