MAB5216
Anti-NMDAR2A Antibody
Chemicon®, from mouse
Synonyme(s) :
NR2A
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
affinity purified immunoglobulin
Clone
monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
Isotype
IgG1
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... GRIN2A(2903)
Immunogène
Amino acid region 1099-1213 from human NMDAR2A produced as a GST fusion protein.
Application
Anti-NMDAR2A Antibody detects level of NMDAR2A & has been published & validated for use in IH(P), IC, IH & WB.
Immunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue: 2.5-5 μg/mL.
Immunocytochemistry: 2.5-5.0μg/mL
Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
Immunocytochemistry: 2.5-5.0μg/mL
Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Liaison
Replaces: MAB5218
Forme physique
Affinity purified immunoglobulin. Liquid in PBS. Contains no preservative.
Format: Purified
Stockage et stabilité
Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
En option
Réf. du produit
Description
Tarif
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Regulation of NMDA receptors by cyclin-dependent kinase-5.
Li, BS; Sun, MK; Zhang, L; Takahashi, S; Ma, W; Vinade, L; Kulkarni, AB; Brady, RO; Pant, HC
Proceedings of the National Academy of Sciences of the USA null
Andre Fischer et al.
Neuron, 48(5), 825-838 (2005-12-13)
While deregulation of cyclin-dependent kinase 5 (Cdk5) has been implicated in neurodegenerative diseases, its precise role in synaptic plasticity and memory remains elusive. Proteolytic cleavage of p35, a regulatory subunit of Cdk5, by calpain results in the generation of the
Ruifa Mi et al.
Neuron, 44(2), 335-349 (2004-10-12)
Under standard conditions, cultured ventral spinal neurons cluster AMPA- but not NMDA-type glutamate receptors at excitatory synapses on their dendritic shafts in spite of abundant expression of the ubiquitous NMDA receptor subunit NR1. We demonstrate here that the NMDA receptor
Céline Bidoret et al.
Frontiers in synaptic neuroscience, 7, 1-1 (2015-03-10)
N-methyl-D-aspartate receptors (NMDARs) in cerebellar molecular layer interneurons (MLIs) are expressed and activated in unusual ways: at parallel fibre (PF) synapses they are only recruited by repetitive stimuli, suggesting an extrasynaptic location, whereas their activation by climbing fibre is purely
Young-A Lee et al.
The European journal of neuroscience, 34(3), 426-436 (2011-06-23)
Chronic stress causes various detrimental effects including cognitive and affective dysfunctions. Given the recent findings emphasizing the importance of information processing between the prefrontal cortex (PFC) and limbic structures on cognitive and affective functions, impairments of these functions caused by
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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