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Key Documents

ABN477

Sigma-Aldrich

Anti-OTUD4 Antibody

from rabbit, purified by affinity chromatography

Synonyme(s) :

OTU domain-containing protein 4, HIV-1-induced protein HIN-1, OTUD4

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

human

Technique(s)

immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... OTUD4(54726)

Description générale

OTU domain-containing protein 4 (OTUD4) is a member of the OTU (ovarian tumor) domain containing cysteine protease superfamily, in which the OTU domain generally confers deubiquitinase activity. High levels of OTUD4 are found in lung, ovary, testis, liver, heart skeletal muscle, kidney, and brain, with lower levels present in pancreas and spleen. Four isoforms of OTUD4 are known to exist, the shortest one being expressed specifically in HIV-1-infected cells.

Immunogène

KLH-conjugated linear peptide corresponding to human OTUD4.

Application

Detect OTU domain-containing protein 4 using this rabbit polyclonal antibody, Anti-OTUD4 Antibody validated for use in western blotting, ICC & Immunofluorescence.
Immunocytochemistry Analysis: 2.5 µg/mL from a representative lot detected OTUD4 in Daudi cells.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected OTUD4 in Daudi cells.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Qualité

Evaluated by Western Blotting in Daudi cell lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected OTUD4 in 15 µg of Daudi cell lysate.

Description de la cible

~108 kDa observed. Uniprot describes four isoforms at ~17 kDa, ~24 kDa, ~117 kDa, and ~124 kDa Uncharacterized bands may appear in some lysates.

Forme physique

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Daudi cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Zhiqiang Wu et al.
Cancer cell international, 19, 99-99 (2019-04-24)
Radiotherapy is becoming one major therapeutics for non-small cell lung cancer (NSCLC). Identifying novel radiosensitizers will greatly increase the efficacy of radiotherapy and benefit more patients. OTU deubiquitinase 4 (OTUD4) has been reported involved in DNA damage repair pathways and

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