06-1376

Anti-SLBP Antibody

serum, from rabbit

• Synonyme(s) : Histone stem-loop-binding protein, hairpin binding protein, histone binding protein 2, histone stem-loop binding protein, stem-loop (histone) binding protein, stem-loop binding protein, HBP, Histone RNA hairpin-binding protein
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: serum
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: mouse, human
• Réactivité de l'espèce (prédite par homologie): rat
• Technique(s): immunocytochemistry: suitable; western blot: suitable
• Numéro d'accès NCBI: NM_009193
• Numéro d'accès UniProt: P97440
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... SLBP(7884)

Description

Description générale

The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3′ end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Spécificité

Antibody recognizes SLBP.

Immunogène

KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP.

Application

Immunocytochemistry:
Representative lot data.
Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus.

Research Sub Category
RNA Metabolism & Binding Proteins

Histones

Use Anti-SLBP Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect SLBP also known as Histone stem-loop-binding protein, HBP, Histone RNA hairpin-binding protein.

Qualité

Evaluated by Western Blotting in C2C12 cell lysates.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates.

Description de la cible

38 kDa

Forme physique

Serum in buffer containing 0.05% sodium azide

Remarque sur l'analyse

Control
C2C12 cell lysates.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1