This product is a sterile, concentrated cell culture supernatant available in a 1 mL volume. The concentration is lot specific, but typically runs at approximately 60 ug/mL. The working concetration is reported on the Certificate of Analysis. T cell activation is tested using Jurkat cells and recent lots report an optimum working concentration of 0.5 ug/mL. Please see the link below to review the available Certificates of Analysis:
https://www.emdmillipore.com/product/Anti-T-Cell-Receptor-Antibody-clone-C305,MM_NF-05-919?ReferrerURL=https%3A%2F%2Fmaestro.lightning.force.com%2F#anchor_COA
05-919
Anti-T-Cell Receptor Antibody, clone C305
culture supernatant, clone C305, Upstate®
Synonyme(s) :
T-Cell receptor antibody
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
culture supernatant
Type de produit anticorps
primary antibodies
Clone
C305, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Upstate®
Technique(s)
immunoprecipitation (IP): suitable
multiplexing: suitable
Isotype
IgM
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... TRDD3(28523)
Spécificité
Jurkat T-Cell Receptor
Immunogène
Jurkat T cells
Application
Anti-T-Cell Receptor Antibody, clone C305 detects level of T-Cell Receptor & has been published & validated for use in Mplex & IP.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
Qualité
routinely used in bioassays to activate T cell receptor signaling cascades in Jurkat cells
Forme physique
Concentrated culture supernatant
Stockage et stabilité
stable 2 years at -20°C from date of shipment
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Pussadee Paensuwan et al.
Journal of immunology (Baltimore, Md. : 1950), 196(1), 448-458 (2015-11-22)
Ligand binding to the TCR causes a conformational change at the CD3 subunits to expose the CD3ε cytoplasmic proline-rich sequence (PRS). It was suggested that the PRS is important for TCR signaling and T cell activation. It has been shown
Nadia Martinez-Martin et al.
Nature communications, 7, 11473-11473 (2016-05-06)
Viruses encode secreted and cell-surface expressed proteins essential to modulate host immune defenses and establish productive infections. However, to date there has been no systematic study of the extracellular interactome of any human virus. Here we utilize the E3 proteins
A Weiss et al.
The Journal of experimental medicine, 160(5), 1284-1299 (1984-11-01)
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat. The molecule with which this
Joseph Lin et al.
The Journal of cell biology, 162(4), 673-682 (2003-08-13)
CD148 is a receptor-like protein tyrosine phosphatase up-regulated on T cells after T cell receptor (TCR) stimulation. To examine the physiologic role of CD148 in TCR signaling, we used an inducible CD148-expressing Jurkat T cell clone. Expression of CD148 inhibits
Monica L Friedrich et al.
The Journal of biological chemistry, 282(7), 4573-4584 (2006-12-22)
Death-associated protein-related apoptotic kinase-2 (DRAK2), a member of the death-associated protein-like family of serine/threonine kinases, is highly expressed in lymphoid organs and is a negative regulator of T cell activation. To investigate the regulation of DRAK2 activity in primary lymphocytes
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Hi, What is the quantity of the antibody and how is it dissolved? We would like to use it for stimulation assays and it should be cell culture suitable.
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