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N-073

Supelco

Nimetazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C16H13N3O3
Numéro CAS:
2011-67-8
Poids moléculaire :
295.29
Numéro MDL:
MFCD00242916
Code UNSPSC :
41116107
ID de substance PubChem :
329818453
Nomenclature NACRES :
NA.24
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

Concentration

1.0 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

clinical testing

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

CN1C(=O)CN=C(c2ccccc2)c3cc(ccc13)[N+]([O-])=O

InChI

1S/C16H13N3O3/c1-18-14-8-7-12(19(21)22)9-13(14)16(17-10-15(18)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

Clé InChI

GWUSZQUVEVMBPI-UHFFFAOYSA-N

Catégories apparentées

Description générale

Nimetazepam, marketed as the benzodiazepine drug Erimin, is prescribed for the treatment of stress or short-term severe insomnia in patients who have difficulty falling asleep or maintaining sleep. Cases of abuse have been reported from Southeast Asian countries including Thailand, Malaysia, Singapore, and Hong Kong to states such as Alabama and North Carolina. Although not used therapeutically in the US, the drug is known for its use to soften the comedown after use of methamphetamine or other stimulants.

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

A-098

7-Aminonimetazepam solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-913

7-Aminonitrazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

IMF-020S

iMethod Test Kit for Benzodiazepines with Synthetic Urine, kit of 23 × 1.0 mL ampules, certified reference material, Cerilliant®

F-907

Flunitrazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

F-915

Flunitrazepam-d7, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-901

Nitrazepam-d5, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

N-906

Nitrazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

N-131

Nimetazepam-D3 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

T Yotsuyanagi et al.
Clinical and experimental dermatology, 23(3), 113-115 (1998-12-23)
The case is presented of a 34-year-old woman with rhabdomyolysis due to massive intake of nimetazepam, a benzodiazepine hypnotic. On admission, the patient had numerous blisters all over the body. One of the blisters in the gluteal region developed into
K Schölermann et al.
Beitrage zur gerichtlichen Medizin, 48, 657-665 (1990-01-01)
The article describes analytical data for the screening and detection of nimetazepam and its major metabolites. The methods comprise thin-layer chromatography, gas chromatography, UV-spectrophotometry, infrared- and mass spectrometry.
N Inotsume et al.
Journal of pharmaceutical sciences, 69(11), 1331-1334 (1980-11-01)
Hydrolytic reactions of nimetazepam and nitrazepam in acidic solutions at body temperature were studied spectrophotometrically. The open-ring compounds produced by hydrolysis were in equilibrium with the corresponding closed-ring compounds (protonated nimetazepam and nitrazepam). Forward-reaction rate constants of both drugs were
H Saito et al.
Research communications in chemical pathology and pharmacology, 52(3), 295-304 (1986-06-01)
In this study, we investigated whether the intensity in the embryotoxicity of benzodiazepines was related to maternal and fetal blood levels and also to their high binding to the fetoplacental structures in rats. Maternal and fetal levels of nitrazepam (NTZ)
[A case of acute glutethimide poisoning].
M Yao et al.
Masui. The Japanese journal of anesthesiology, 31(9), 1035-1040 (1982-09-01)
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