C-035

(±)-Cotinine-d₃ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonyme(s) : (+/-)-Cotinine-d₃ solution
• Formule empirique (notation de Hill): C₁₀H₉D₃N₂O
• Numéro CAS: 110952-70-0
• Poids moléculaire : 179.23
• Numéro CE : 200-659-6
• Numéro MDL: MFCD00083283
• Code UNSPSC : 41116107
• ID de substance PubChem : 329774776
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 1.0 mg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): forensics and toxicology
• Format: single component solution
• Température de stockage: −20°C
• InChI: 1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3
• Clé InChI: UIKROCXWUNQSPJ-FIBGUPNXSA-N

Description

Description générale

Cotinine is an alkaloid found in tobacco as well as a major urinary metabolite of nicotine. This stable-labeled internal standard is suitable for quantitation of cotinine levels in urine, blood, and saliva for GC/MS or LC-MS/MS applications in nicotine testing or clinical and diagnostic testing of nicotine biomarkers.

Application

• (±)-Cotinine-d₃ solution in nicotine metabolism research: This stable isotope-labeled compound is utilized in the HPLC-MS analysis of nicotine and cotinine across various biological matrices, highlighting its critical role in advancing our understanding of nicotine metabolism and exposure in biomedical studies (Jin et al., 2022).


• Biomarker analysis in passive smoking: Cotinine-d₃ serves as an internal standard in the precise quantification of urinary cotinine, aiding in the assessment of second-hand smoke exposure, particularly in pediatric health studies (Wang et al., 2014).


• Enhanced analytical techniques for smoking cessation: Employed in a sophisticated UPLC-MS/MS setup, cotinine-d₃ is crucial for quantifying smoking-related biomarkers in clinical trials aimed at evaluating smoking cessation interventions, ensuring accurate and sensitive biomarker tracking (Dobrinas et al., 2011).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 51.8 °F - closed cup
• Point d'éclair (°C): 11.0 °C - closed cup