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Key Documents

790427P

Avanti

06:0 PC-d22

Avanti Research - A Croda Brand 790427P, powder

Synonyme(s) :

1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine

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About This Item

Formule empirique (notation de Hill):
C20H18NO8PD22
Numéro CAS:
Poids moléculaire :
475.64
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 10 mg (790427P-10mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand 790427P

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) is a hydrophobic acyl chain containing phospholipid with a critical micelle concentration of 15 mM. 06:0 PC-d22 is the deuterated form of 06:0 PC.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

06:0 PC-d22 has been used in small isotropic bicelles preparation for C-peptide membrane interaction studies by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY) and in in situ infrared (IR) absorption spectra. It may be used as an internal standard in capillary electrophoresis time of flight mass spectrometer (CE-TOFMS) and liquid chromatography with tandem mass spectrometry (LC-MS-MS) for the analysis of algal lipidome.

Actions biochimiques/physiologiques

1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) bicelle with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) takes a disc like conformation. Phosphocholine (PC) is the catabolized product of phosphatidylcholine (lecithin). PC mediates immune response and acts as a ligand for nicotinic acetylcholine receptors (nAChR).

Conditionnement

5 mL Clear Glass Sealed Ampule (790427P-10mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Sofia Unnerståle et al.
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012, 185907-185907 (2012-08-01)
C-peptide is the connecting peptide between the A and B chains of insulin in proinsulin. In this paper, we investigate the interaction between C-peptide and phospholipid bicelles, by circular dichroism and nuclear magnetic resonance spectroscopy, and in particular the pH
Takuro Ito et al.
Metabolomics : Official journal of the Metabolomic Society, 9(Suppl 1), 178-187 (2013-03-07)
Oil-rich algae have promising potential for a next-generation biofuel feedstock. Pseudochoricystis ellipsoidea MBIC 11204, a novel unicellular green algal strain, accumulates a large amount of oil (lipids) in nitrogen-deficient (-N) conditions. Although the oil bodies are easily visualized by lipophilic
Soichiro Matsunaga et al.
Langmuir : the ACS journal of surfaces and colloids, 33(46), 13157-13167 (2017-08-02)
In situ dynamic observation of model biological cell membranes, formed on a water/gold substrate interface, has been performed by the combination of electrochemical scanning tunneling microscopy and reflection infrared absorption vibrational spectroscopy. Monolayers of 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) were formed on alkanethiol-modified
K Richter et al.
Scientific reports, 6, 28660-28660 (2016-06-29)
We demonstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhibit ATP-dependent release of interleukin-1β from human and murine monocytes by a mechanism involving nicotinic acetylcholine receptors (nAChR). Interleukin-1β is a potent pro-inflammatory cytokine of innate immunity that plays pivotal roles
Systematic Characterization of DMPC/DHPC Self-Assemblies and Their Phase Behaviors in Aqueous Solution
Taguchi S, et al.
Colloids and Interfaces, 2(4), 73-73 (2018)

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