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Key Documents

W228826

Sigma-Aldrich

trans-Cinnamic acid

greener alternative

natural, ≥99%, FCC, FG

Synonyme(s) :

trans-3-Phenylacrylic acid, Cinnamic acid

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About This Item

Formule linéaire :
C6H5CH=CHCOOH
Numéro CAS:
Poids moléculaire :
148.16
Numéro FEMA:
2288
Numéro Beilstein :
1905952
Numéro CE :
Conseil de l'Europe Nº :
22c
Numéro MDL:
Code UNSPSC :
12164502
ID de substance PubChem :
Numéro Flavis :
8.022
Nomenclature NACRES :
NA.21

Qualité

FG
Fragrance grade
Halal
Kosher
natural

Niveau de qualité

Agence

follows IFRA guidelines

Conformité réglementaire

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117

Pureté

≥99%

Caractéristiques du produit alternatif plus écologique

Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Point d'ébullition

300 °C (lit.)

Pf

132-135 °C (lit.)

Application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

Allergène alimentaire

no known allergens

Allergène de parfum

no known allergens

Autre catégorie plus écologique

Propriétés organoleptiques

cinnamon; honey; spicy; floral; sweet

Chaîne SMILES 

OC(=O)\C=C\c1ccccc1

InChI

1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+

Clé InChI

WBYWAXJHAXSJNI-VOTSOKGWSA-N

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Description générale

trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. It is mainly used to prepare ester derivatives that are used in perfume industry. trans-Cinnamic acid is the key volatile components of cinnamon essential oil.
We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product is a Biobased products, showing key improvements in Green Chemistry Principles “Less Hazardous Chemical Syntheses” and “Use of Renewable Feedstock”.

Application


  • Single-Cell Oral Delivery Platform for Enhanced Acid Resistance and Intestinal Adhesion.: This research utilizes trans-cinnamic acid in developing a novel oral delivery system that enhances acid resistance and intestinal adhesion, offering significant advancements in pharmaceutical and biomedical applications (Wei et al., 2024).

  • The evaluation of L-arginine solution as a solvent for propolis extraction: The phenolic profile, antioxidant, antibacterial activity, and in vitro bioaccessibility.: Highlighting the solvent properties of trans-cinnamic acid, this study provides insights into its use in extracting bioactive compounds from natural sources, contributing to advancements in food science and nutraceuticals (Mergen Duymaz et al., 2024).

  • Characterization of cinnamate 4-hydroxylase (CYP73A) and p-coumaroyl 3′-hydroxylase (CYP98A) from Leucojum aestivum, a source of Amaryllidaceae alkaloids.: This research uses trans-cinnamic acid to study enzyme activity in plant biosynthesis pathways, providing valuable information for the development of bioengineering strategies to synthesize natural products (Karimzadegan et al., 2024).

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

320.0 °F - closed cup

Point d'éclair (°C)

160 °C - closed cup

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Analysis of the trans-Cinnamic Acid Content in Cinnamomum spp. and Commercial Cinnamon Powder Using HPLC
Lee J, et al
Journal of Agricultural Chemistry and Environment, 4(04), 102-102 (2015)
Aqueous solubility of some natural phenolic compounds
Mota FL, et al
Industrial & Engineering Chemistry Research, 47(15), 5182-5189 (2008)
Encyclopedia of Food and Color Additives, 1, 592-593 (1997)
Bianca C Pérez et al.
Journal of medicinal chemistry, 56(2), 556-567 (2013-01-01)
The control of malaria is challenged by drug resistance, and new antimalarial drugs are needed. New drug discovery efforts include consideration of hybrid compounds as potential multitarget antimalarials. Previous work from our group has demonstrated that hybrid structures resulting from
Andrew M Lauer et al.
Organic letters, 14(19), 5138-5141 (2012-09-25)
A highly regioselective, Pd-catalyzed allylic fluorination of phosphorothioate esters is reported. This chemistry addresses several limitations of previously reported methods in which elimination and lack of reactivity were problematic. Preliminary mechanistic investigations reveal that these reactions are stereospecific and provide

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