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Principaux documents

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38534

Sigma-Aldrich

Polylactic acid

Mw ~60,000

Synonyme(s) :

Poly(2-hydroxypropionic acid)

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About This Item

Numéro CAS:
26100-51-6
Numéro MDL:
MFCD00081867
Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Forme

solid

Niveau de qualité

100

Durée de conservation

limited shelf life, expiry date on the label

Poids mol.

Mn ~30,000
Mw ~60,000

Chaîne SMILES 

[O-]C(=O)C(O)C.[H+]

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

Clé InChI

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

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Description générale

Polylactic acid(PLA) is a biodegradable polyester synthesized from lactic acid monomer via ring opening polymerization. Owing to its excellent thermal, mechanical and barrier properties, it is widely used in the field of tissue engineering, drug delivery, and orthopedic devices.

Application

Polylactic acid can be used to prepare tubular scaffolds via the electrospinning method. These scaffolds are applicable in vascular tissue engineering.

It can be used to prepare PLA/polyvinyl alcohol wound dressing membrane through electrospinning and coating method. The coating of PLA improves the mechanical strength of nanofiber and acts as a protective layer to control the release of drug to the wound site.

It can also be used to synthesize free-standing, flexible ultra-thin PLA nanofilms which can act as a matrix for adhesion, spreading, and proliferation of skeletal muscle cells.

Caractéristiques et avantages

  • Biocompatibility
  • Lower toxicity
  • Low cost
  • Better encapsulation

Produit(s) apparenté(s)

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NanoFabTx™ microfluidic - nano, device kit for synthesis of 100-200 nm nanoparticles and liposomes

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NanoFabTx™ PLGA-micro, for synthesis of 10-30 um particles

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCM8146
BCCM8144
BCCM4836
BCCM4837
BCCM1900

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Poly L Lactic Acid - Biopolymer (PLLA), film, thickness 0.05 mm, L 0.5 m, condition biopolymer

GF27769304

Poly L Lactic Acid - Biopolymer

Polyglycolide inherent viscosity 1.4dL/g

Sigma-Aldrich

457620

Polyglycolide

Poly(L-lactide) viscosity ~2.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

81273

Poly(L-lactide)

Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

Tong Chen et al.
Carbohydrate polymers, 92(2), 1124-1132 (2013-02-13)
Core-shell structured multifunctional nanocarriers (NCs) of ZnO quantum dots-conjugated gold nanoparticles (Au NPs) as core and amphiphilic hyperbranched block copolymer as shell were synthesized for targeted anticancer drug delivery. The amphiphilic hyperbranched block copolymer contained poly(l-lactide) (PLA) inner arm and
Discussion: Autologous fat grafting and injectable dermal fillers for human immunodeficiency virus-associated facial lipodystrophy: a comparison of safety, efficacy, and long-term treatment outcomes.
David Teplica
Plastic and reconstructive surgery, 131(3), 507-509 (2013-03-01)
Zhenxing Fan et al.
Environmental technology, 33(19-21), 2369-2374 (2013-02-12)
Biological nitrate removal using wheat straw and polylactic acid (PLA) as both carbon source and biofilm support was investigated. The results showed that biofilm could develop on the surface of wheat straw within 15 d, the denitrification rate was 0.067
L Pearce McCarty et al.
The Journal of bone and joint surgery. American volume, 95(6), 507-511 (2013-02-15)
A variety of complications associated with the use of poly-L-lactic acid (PLLA) implants, including anchor failure, osteolysis, glenohumeral synovitis, and chondrolysis, have been reported in patients in whom these implants were utilized for labral applications. We report on a large
Huan Zhou et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2302-2310 (2013-03-19)
Fibrous bionanocomposites consisting of amorphous magnesium phosphate (AMP) nanospheres and polylactic acid (PLA) were fabricated by electrospinning. There are two important signatures of this paper. First, AMP, as an alternative to well-known calcium phosphate (CaP) materials, is added to PLA
Afficher tous les articles scientifiques apparentés

Articles

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

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