1605205

Ropinirole hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride, SKF 101468 hydrochloride
• Formule empirique (notation de Hill): C₁₆H₂₄N₂O · HCl
• Numéro CAS: 91374-20-8
• Poids moléculaire : 296.84
• Numéro MDL: MFCD01754173
• Code UNSPSC : 41116107
• ID de substance PubChem : 329751058
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: ropinirole
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: Cl.CCCN(CCC)CCc1cccc2NC(=O)Cc12
• InChI: 1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H,3-4,8-12H2,1-2H3,(H,17,19);1H
• Clé InChI: XDXHAEQXIBQUEZ-UHFFFAOYSA-N
• Informations sur le gène: human ... DRD2(1813) , DRD3(1814) , DRD4(1815)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ropinirole hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Ropinirole Extended-Release Tablets
• Ropinirole Hydrochloride
• Ropinirole Tablets

Actions biochimiques/physiologiques

An agonist at the D₂ and D₃ dopamine receptor subtypes, binding with higher affinity to D₃ than to D₂ or D₄. It has negligible effect on D₁-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT₁, 5-HT₂, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H400
• Conseils de prudence: P301 + P312 + P330
• Classification des risques: Acute Tox. 4 Oral - Aquatic Acute 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable