569250-U
Discovery® HS C18 (3 µm) HPLC Columns
L × I.D. 5 cm × 4.6 mm, HPLC Column
Synonyme(s) :
Discovery RP18 HPLC Column
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About This Item
Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52
Produits recommandés
product name
Colonne HPLC Discovery® HS C18, 3 μm particle size, L × I.D. 5 cm × 4.6 mm
Matériaux
stainless steel column
Agence
suitable for USP L1
Gamme de produits
Discovery®
Caractéristiques
endcapped
Fabricant/nom de marque
Discovery®
Conditionnement
1 ea of
Ampleur du marquage
20% Carbon loading
Paramètres
≤70 °C temp. range
400 bar pressure (5801 psi)
Technique(s)
HPLC: suitable
LC/MS: suitable
L × D.I.
5 cm × 4.6 mm
Superficie
300 m2/g
Couverture de surface
3.2 μmol/m2
Impuretés
<10 ppm metals
Matrice
silica gel, high purity, spherical particle platform
fully porous particle
Groupe de la matrice active
C18 (octadecyl) phase
Taille des particules
3 μm
Dimension de pores
120 Å
operating pH range
2-8
Application(s)
food and beverages
Technique de séparation
reversed phase
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Catégories apparentées
Application
- A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This study developed a robust RP-HPLC method to determine molnupiravir in various nanoformulations, showcasing its potential application in permeability studies and ensuring drug stability (Reçber et al., 2022) (Reçber et al., 2022).
- Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: This research presented an HPLC-UV method for analyzing terizidone in plasma, facilitating its use in pharmacokinetic studies of patients with drug-resistant tuberculosis (Mulubwa and Mugabo, 2018) (Mulubwa and Mugabo, 2018).
- Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: The study optimized an LC method for quantifying doxorubicin in plasma and urine, crucial for pharmacokinetic, biomedical, and drug monitoring therapy applications (Maliszewska et al., 2018) (Maliszewska et al., 2018).
Caractéristiques et avantages
- Stables, faible relargage pour applications LC-MS
- Changement d′échelle de l′analytique à la préparative
- Haute stabilité pour assurer une excellente reproductibilité d′injection à injection et de lot à lot
- Hydrophobicité plus élevée pour une meilleure résolution des analytes difficiles
Informations légales
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Colonne de garde
Réf. du produit
Description
Tarif
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Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
Jolanta Flieger et al.
Journal of separation science, 34(7), 733-739 (2011-03-02)
Highly hydrophilic compounds belonging to biogenic amines were analysed in the reversed-phase system, modified with the addition of ionic liquids: 1-ethyl-3-methyl-imidazolium hexafluorophosphate (EMIM PF(6)) and chaotropic salt NaPF(6) on Discovery HS C18 column at acidic conditions. The effect of the
Bhavin N Patel et al.
Biomedical chromatography : BMC, 22(11), 1213-1224 (2008-07-25)
A simple, precise and accurate assay for the determination of 6-methoxy-2-naphthylacetic acid (6-MNA), an active metabolite of nabumetone in human plasma, was developed and validated using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The analyte (6-MNA) and propranolol (internal standard, IS) were
Fazli Khuda et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 944, 114-122 (2013-12-10)
A simple, specific, precise and rapid RP-HPLC-UV method was developed for simultaneous determination of lumefantrine and its metabolite desbutyl lumefantrine in human plasma. Experimental parameters were optimized and the method was validated according to standard guidelines. The method showed adequate
Lucie Zelena et al.
Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis
Contenu apparenté
HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.
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