18127

1,1,1,3,3,3-Hexafluoro-2-propanol

for LC-MS LiChropur^™

• Synonyme(s) : HFP, Hexafluoroisopropanol
• Formule linéaire : (CF₃)₂CHOH
• Numéro CAS: 920-66-1
• Poids moléculaire : 168.04
• Numéro Beilstein : 1841007
• Numéro MDL: MFCD00011651
• Code UNSPSC : 12352104
• Nomenclature NACRES : NA.21

Propriétés

• Pureté: ≥99.8% (GC)
• Forme: liquid
• Qualité: for LC-MS LiChropur^™
• Impuretés: ≤0.02% water
• Indice de réfraction: n20/D 1.275 (lit.)
• Point d'ébullition: 59 °C (lit.)
• Pf: −4 °C (lit.)
• Densité: 1.596 g/mL at 25 °C (lit.)
• Traces de cations: Al: ≤0.5 ppm; Ca: ≤0.5 ppm; Cu: ≤0.02 ppm; Fe: ≤0.1 ppm; K: ≤2 ppm; Mg: ≤0.1 ppm; Na: ≤10 ppm
• Adéquation: passes test for LC-MS (ESI/APCI pos. < 10 ppb)
• Chaîne SMILES: OC(C(F)(F)F)C(F)(F)F
• InChI: 1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H
• Clé InChI: BYEAHWXPCBROCE-UHFFFAOYSA-N

Description

Description générale

1,1,1,3,3,3-Hexafluoro-2-propanol(HFIP) is a thermally stable, highly polar, UV-transparent solvent that is misciblewith water and many polar organic solvents. It is used as a mobile phaseadditive in liquid chromatography-mass spectrometry (LC-MS) method to improveseparation and detection.

Application

1,1,1,3,3,3-Hexafluoro-2-propanol can be used as a:

• Buffer additive for LC-ESI-MS to separate acidic and basic compounds.
• Eluent additive in the UHPLC-MS/MS method to improve the chromatographic separation of basic and zwitterionic compounds.

Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS08,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H314,H361fd,H373
• Conseils de prudence: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2 Oral
• Organes cibles: Central nervous system
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): No data available
• Point d'éclair (°C): No data available