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RAB0715

Sigma-Aldrich

Human MB / Myoglobin ELISA Kit

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable

Entrée

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.82 ng/mL
standard curve range: 0.819-200 ng/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... MB(4151)

Description générale

The MB ELISA kit provides for the Quantitative measurement of Myoglobin in Cell Culture Supernatants, Plasma and Serum.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Actions biochimiques/physiologiques

Myoglobin is a hemoprotein that regulates the storage and diffusion of oxygen in heart and skeletal muscles. It also protects the tissues from oxidative damage by controlling the levels of reactive oxygen species and nitric oxide. Myoglobin modulates nitric oxide and oxygen levels in the mitochondrial compartments of skeletal muscle and cardiac cells.

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS

  • RABSTOP3ELISA Stop Solution (Item I)FDS

  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion

Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Xiaoyun Liu et al.
International journal of cardiology, 296, 129-135 (2019-08-24)
The therapeutic potential of doxorubicin (DOX) is limited by cardiotoxicity. Rubicon is an inhibitory interacting partner of autophagy protein UVRAG. Currently, the role of Rubicon in DOX-induced cardiotoxicity is unknown. In this study, we test the hypothesis that loss of
Myoglobin: an essential hemoprotein in striated muscle.
Ordway GA, et al.
The Journal of Experimental Biology, 207(20), 3441-3446 (2004)
Lin An et al.
Scientific reports, 7, 43251-43251 (2017-02-23)
Doxorubicin (DOX) is an effective chemotherapeutic drug in the treatment of various types of cancers. However, its clinical application has been largely limited by potential development of cardiotoxicity. Previously we have shown that ultra-violet radiation resistance-associated gene (UVRAG), an autophagy-related
Unmasking the Janus face of myoglobin in health and disease.
Hendgen-Cotta UB, et al.
The Journal of Experimental Biology, 213(16), 2734-2740 (2010)
Fangfei Li et al.
Nature communications, 8(1), 1390-1390 (2017-11-11)
Paclitaxel (PTX) is among the most commonly used first-line drugs for cancer chemotherapy. However, its poor water solubility and indiscriminate distribution in normal tissues remain clinical challenges. Here we design and synthesize a highly water-soluble nucleolin aptamer-paclitaxel conjugate (NucA-PTX) that

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