G2785

Glycitein

≥97% (HPLC)

• Synonyme(s) : 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
• Formule empirique (notation de Hill): C₁₆H₁₂O₅
• Numéro CAS: 40957-83-3
• Poids moléculaire : 284.26
• Numéro MDL: MFCD00016679
• Code UNSPSC : 41106305
• ID de substance PubChem : 329799906
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic (organic)
• Pureté: ≥97% (HPLC)
• Forme: powder
• Solubilité: DMF: 1 mg/mL, clear, colorless to faintly yellow
• Température de stockage: −20°C
• Chaîne SMILES: COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3
• InChI: 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
• Clé InChI: DXYUAIFZCFRPTH-UHFFFAOYSA-N

Description

Application

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Actions biochimiques/physiologiques

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)