F8384

Flavin adenine dinucleotide disodium salt hydrate

BioReagent, suitable for cell culture

• Synonyme(s) : FAD, FAD-Na₂, Riboflavin 5′-adenosine diphosphate disodium salt
• Formule empirique (notation de Hill): C₂₇H₃₁N₉Na₂O₁₅P₂ · xH₂O
• Numéro CAS: 84366-81-4
• Poids moléculaire : 829.51 (anhydrous basis)
• Numéro Beilstein : 5326842
• Numéro MDL: MFCD08277021
• Code UNSPSC : 12352207
• ID de substance PubChem : 24894962
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: bovine milk
• Gamme de produits: BioReagent
• Pureté: ≥95%
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Solubilité: water: 50 mg/mL, clear
• Température de stockage: −20°C
• Chaîne SMILES: [Na+].[Na+].[H]O[H].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)c2cc1C
• InChI: 1S/C27H33N9O15P2.2Na.H2O/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;;1H2/q;2*+1;/p-2/t14-,15+,16+,19-,20+,21+,26+;;;/m0.../s1
• Clé InChI: GXTPHHZYFMAGLX-UJXBNFGUSA-L

Description

Description générale

Flavin adenine dinucleotide (FAD) is a redox cofactor of flavoproteins, such as cytochrome-b₅ reductase enzyme. With the help of nicotinamide adenine dinucleotide phosphate (NADPH), FAD can be reduced to form FADH₂.

Application

Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.

Flavin adenine dinucleotide disodium salt hydrate has been used as a component in the extraction buffer for plant tissue extraction. It has also been used to study its effects on infarct areas of middle cerebral artery occlusion (MCAO) induced mice.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)