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256A-1

Sigma-Aldrich

Gastrin Rabbit Polyclonal Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

Ig fraction of antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (256A-14)
vial of 0.5 mL concentrate (256A-15)
bottle of 1.0 mL predilute (256A-17)
vial of 1.0 mL concentrate (256A-16)
bottle of 7.0 mL predilute (256A-18)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Contrôle

stomach

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic

Informations sur le gène

human ... GAST(2520)

Catégories apparentées

Description générale

Gastrin is a polypeptide hormone produced by G-cells in the gastric antrum and duodenal mucosa that serves as an important regulator of gastric acid secretion. Gastrin is useful for the identification of gastrin-secreting non-neoplastic and neoplastic neuroendocrine cells. Anti-Gastrin antibody gives positive staining of G-cells of human antral/pyloric mucosa and cells producing gastrin or a structural gastrin analogue as is seen in the stomach; no staining of other cells or tissue types has been observed. This antibody may react with sulfated and non-sulfated forms of gastrin. The antibody cross-reacts with more than 50% of the present choleocystokinin octapeptide.

Qualité


IVD
IVD
IVD
RUO

Liaison

Gastrin (polyclonal) Positive Control Slides, Product No. 256S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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J Müller et al.
The American journal of surgical pathology, 11(12), 909-917 (1987-12-01)
Immunohistochemical, histochemical, and morphometrical studies of six gastric carcinoid tumors and their possible precursor lesions in gastric mucosa are reported. All tumors, presenting successively at our institute, occurred in the corpus mucosa of 45- to 78-year-old patients. Two neoplasms had
L Bornstein-Quevedo et al.
Human pathology, 32(11), 1252-1256 (2001-12-01)
Carcinoid tumors of the ampulla of Vater (ACs) differ from duodenal carcinoid tumors (DCs). A search for AC and DC was made between 1980 and 2000. The clinicopathologic features and follow-up were assessed. Immunohistochemistry for panneuroendocrine markers, hormone products, proliferating
M E Herrmann et al.
Archives of pathology & laboratory medicine, 124(6), 832-835 (2000-06-03)
The term primary lymph node gastrinoma was first used to describe a group of patients with gastrin-producing tumors present in lymph nodes located in a well-defined anatomic region. The patients had no known primary tumors in the pancreas or gastrointestinal
J F Rehfeld et al.
The Journal of biological chemistry, 256(20), 10426-10429 (1981-10-25)
The anterior, intermediate, and neural lobes of porcine pituitaries contain different molecular forms of gastrin. In the anterior lobe, unsulfated large gastrins, component I, and gastrin-34 constitute the main forms. In contrast in the intermediate and neural lobes, gastrin-17, sulfated
Expression of gastrin and its receptor in human gastric cancer tissues.
Hur, Keun et al
Journal of Cancer Research and Clinical Oncology, 132,2, 85-91 (2006)
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