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Principaux documents

22040

Sigma-Aldrich

β-Carotene

≥97.0% (UV)

Synonyme(s) :

β,β-Carotene, Provitamin A

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About This Item

Formule empirique (notation de Hill):
C40H56
Numéro CAS:
Poids moléculaire :
536.87
Beilstein:
1917416
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352200
ID de substance PubChem :
Nomenclature NACRES :
SB.54

Source biologique

synthetic

Essai

≥97.0% (UV)

Forme

powder

Technique(s)

HPLC: suitable

Impuretés

≤0.001% heavy metals

Perte

≤0.2% loss on drying

Couleur

red to dark red

Pf

176-184 °C (dec.)

Solubilité

chloroform: 10 mg/mL, clear, dark orange-red

Conditions d'expédition

dry ice

Température de stockage

2-8°C

Chaîne SMILES 

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+

Clé InChI

OENHQHLEOONYIE-JLTXGRSLSA-N

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Application

  • β-Carotene has been used as a standard to measure β-carotene levels in plasma samples via HPLC (high performance liquid chromatography).[1]
  • It has been used to study the effects of vitamins on growth of Mycobacteria in radiometric culture.[2]
  • It has been used as a supplement in the growth medium of Drosophila melanogaster to allow intake of vitamin A.[3]

Actions biochimiques/physiologiques

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.
The most important of the provitamins A.

Attention

Purchase minimum quantity required. Discard one month after opening.

Autres remarques

As a probe of lipid domains of reconstituted human plasma low-density lipoprotein[4]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

217.9 °F - closed cup

Point d'éclair (°C)

103.3 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves


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Les clients ont également consulté

G C Chen et al.
Biochemistry, 19(20), 4706-4712 (1980-09-30)
Mixtures of neutral lipids containing cholesteryl esters and beta-carotene were used to reconstitute the lipid core of heptane-extracted low-density lipoproteins (LDL). The resulting preparations of reconstituted LDL, referred to as r-[cholesteryl ester + beta-carotene]LDL, exhibited temperature-dependent circular dichroism (CD) in
Lack of Dietary Polyunsaturated Fatty Acids Causes Synapse Dysfunction in the Drosophila Visual System.
Ziegler AB, et al.
PLoS ONE, 10, e0135353-e0135353 (2015)
Vitamins A & D inhibit the growth of mycobacteria in radiometric culture.
Greenstein RJ, et al.
PLoS ONE, 7, e29631-e29631 (2012)
Kyeongjin Kim et al.
Experimental & molecular medicine, 41(6), 429-439 (2009-03-27)
Small heterodimer partner (SHP) is an atypical member of nuclear receptor superfamily that lacks a DNA-binding domain. In previous study, we showed that SHP, c-jun, p65 of NF-gammaB subunits, and p21WAF1 expression was increased during monocytic differentiaton with the exposure
Antonio Molino et al.
Molecules (Basel, Switzerland), 24(4) (2019-02-24)
Microalgae Dunaliella salina contains useful molecules such as β-carotene and fatty acids (FAs), which are considered high value-added compounds. To extract these molecules, supercritical carbon dioxide was used at different operative conditions. The effects of mechanical pre-treatment (grinding speed at

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