T4375

Tetrazolium Blue Chloride

used in colorimetric determination of reducing compounds

• Synonyme(s) : 3,3′-(3,3′-Dimethoxy[1,1′-biphenyl]-4,4′-diyl)-bis(2,5-diphenyl-2H-tetrazolium) dichloride, 3,3′-Dianisole-4,4′-bis(3,5-diphenyltetrazolium chloride), BTC, Blue Tetrazolium chloride, TZ
• Formule empirique (notation de Hill): C₄₀H₃₂Cl₂N₈O₂
• Numéro CAS: 1871-22-3
• Poids moléculaire : 727.64
• Beilstein: 3894077
• Numéro CE : 217-488-8
• Numéro MDL: MFCD00040933
• Code UNSPSC : 12171500
• ID de substance PubChem : 24900207
• Nomenclature NACRES : NA.47

Propriétés

• Niveau de qualité: 200
• Forme: powder
• Pf: 255 °C (dec.) (lit.)
• Solubilité: methanol: 50 mg/mL, clear
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: [Cl-].[Cl-].COc1cc(ccc1-[n+]2nc(nn2-c3ccccc3)-c4ccccc4)-c5ccc(c(OC)c5)-[n+]6nc(nn6-c7ccccc7)-c8ccccc8
• InChI: 1S/C40H32N8O2.2ClH/c1-49-37-27-31(23-25-35(37)47-43-39(29-15-7-3-8-16-29)41-45(47)33-19-11-5-12-20-33)32-24-26-36(38(28-32)50-2)48-44-40(30-17-9-4-10-18-30)42-46(48)34-21-13-6-14-22-34;;/h3-28H,1-2H3;2*1H/q+2;;/p-2
• Clé InChI: MUUHXGOJWVMBDY-UHFFFAOYSA-L

Description

Application

Tetrazolium blue chloride (BTC) is a colorless tetrazolium compound that upon reduction forms a colored diformazan.[1] The reactivity has been applied to the analysis of reducing compounds including the nanomolar detection of reducing sugars[2] and carbidopa and methyldopa.[3] BTC has been used for histological staining of mouse coronal brain sections[4] and rat brain sections.[5] In combination with 4-nitrocatechol, tetrazolium blue chloride forms a ternary complex with molybdenum(VI) for extraction and spectrophotometric determination of molybdenum.[6] It has also been used to stain Francisella tularensis cells for tularemic microagglutination test.[7]

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H350
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Carc. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable