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PHR1436

Supelco

Foscarnet Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Foscarnet sodium hexahydrate

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About This Item

Formule empirique (notation de Hill):
CNa3O5P · 6H2O
Numéro CAS:
Poids moléculaire :
300.04
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to BP 623
traceable to Ph. Eur. F0389000
traceable to USP 1283302

Famille d'API

foscarnet

CofA (certificat d'analyse)

current certificate can be downloaded

Conditionnement

pkg of 1 g

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

InChI

1S/CH3O5P.3Na.6H2O/c2-1(3)7(4,5)6;;;;;;;;;/h(H,2,3)(H2,4,5,6);;;;6*1H2/q;3*+1;;;;;;/p-3

Clé InChI

ILRVASBWNRYBFD-UHFFFAOYSA-K

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Description générale

Foscarnet Sodium is a selective inhibitor of herpes simplex virus (HSV). It is an antiviral agent used in the treatment of cytomegalovirun retinitis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA3051 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogrammes

Health hazard

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Muta. 2 - STOT RE 2

Organes cibles

Kidney,Bone

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Efficacy and safety of foscarnet for recurrent orolabial herpes: a multicentre randomized double-blind study.
Lawee D, et al.
CMAJ : Canadian Medical Association Journal = Journal de l'Association Medicale Canadienne, 138(4), 329-329 (1988)
Jocelyne Piret et al.
Journal of virology, 89(8), 4636-4644 (2015-02-13)
DNA polymerases of the Herpesviridae and bacteriophage RB69 belong to the α-like DNA polymerase family. In spite of similarities in structure and function, the RB69 enzyme is relatively resistant to foscarnet, requiring the mutation V478W in helix N to promote

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