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P8074

Sigma-Aldrich

TWEEN® 80

BioXtra, viscous liquid

Synonyme(s) :

Mono-oléate de polyoxy-éthylènesorbitane, Mono-oléate de polyéthylène glycol sorbitane, Monooléate de POE (20)-sorbitane, Polysorbate 80

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About This Item

Numéro CAS:
9005-65-6
Numéro MDL:
MFCD00082107
Code UNSPSC :
12161900
Nomenclature NACRES :
NA.21

Description

non-ionic

Niveau de qualité

200

Gamme de produits

BioXtra

Forme

viscous liquid

Poids mol.

micellar avg mol wt 79,000
average mol wt 1310

Composition

Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)

Nombre d'agrégation

60

Technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

Impuretés

≤0.025% Phosphorus (P)

Résidus de calcination

<0.1%

CMC

0.012 mM (20-25°C)

Température de transition

cloud point 65 °C

Densité

1.06 g/mL at 25 °C

Traces d'anions

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

Traces de cations

Al: <0.0005%
Ca: <0.001%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.05%
Pb: <0.001%
Zn: <0.0005%

HLB

15

Chaîne SMILES 

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

Clé InChI

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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Description générale

["TWEEN"] 80 is a polyethylene sorbitol ester, broadly used in biochemical applications like solubilizing proteins, isolating nuclei from cells in culture, and growing tubercle bacilli. It is also useful in emulsifying and dispersing substances in medicinal and food products. TWEEN 80 acts as an active drying agent in ice cream.

Application

["TWEEN"] 80 has been used:
  • to dissolve rapamycin (RAPA) for immunosuppressive treatment to perform in vivo studies in mice
  • to dissolve remodelin and remodelin Fluor to assess remodelin toxicity in vivo and small molecule dosing
  • to prepare assay medium for the microbiological assay for total folate

Informations légales

TWEEN is a registered trademark of Croda International PLC

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

>235.4 °F - closed cup

Point d'éclair (°C)

> 113 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCL8873
BCCJ7552
BCCH2519
BCCF5441
BCCD6595

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Polysorbate 80 United States Pharmacopeia (USP) Reference Standard

USP

1547969

Polysorbate 80

TWEEN&#174;&nbsp;20 BioXtra, viscous liquid

Sigma-Aldrich

P7949

TWEEN® 20

TWEEN&#174; 80 OmniPur&#174;

Millipore

9490-OP

TWEEN® 80

TWEEN&#174; 80 protein grade detergent, 10% solution, sterile-filtered, for immunoprecipitation and for the solubilization of membrane-bound proteins

Millipore

655207

TWEEN® 80

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Workflow for the Analysis of Polysorbate 80 in Erbitux® Formulation

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

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