91897

Phloretin

analytical standard

• Synonyme(s) : β-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 2′,4′,6′-Trihydroxy-3-(4-hydroxyphenyl)propiophenone, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
• Formule empirique (notation de Hill): C₁₅H₁₄O₅
• Numéro CAS: 60-82-2
• Poids moléculaire : 274.27
• Beilstein: 1887240
• Numéro CE : 200-488-7
• Numéro MDL: MFCD00002288
• Code UNSPSC : 85151701
• ID de substance PubChem : 329770094
• Nomenclature NACRES : NA.24

Propriétés

• Niveau de qualité: 100
• Qualité: analytical standard
• Essai: ≥98.5% (HPLC)
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Impuretés: ≤8.0% water
• Pf: ~260 °C
• Application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
• InChI: 1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
• Clé InChI: VGEREEWJJVICBM-UHFFFAOYSA-N

Description

Description générale

Major polyphenol found in apple; aglycone of phloridzin.

Phloretin is a dihydrochalcone flavonoid with antioxidant activity usually found in apples and apple-derived products.[1][2] It is extensively used for peroxynitrite scavenging and the inhibition of lipid peroxidation.[1]

Application

Phloretin may be used as an internal standard for the determination of sterols and diterpenoids in brown algae using high-performance liquid chromatography (HPLC).[3]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Reacts with vic-dicarbonyl compounds such as glyoxal and methylglyoxal, preventing cytotoxic conjugation with biological macromolecules.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable