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(R)-3-Hydroxybutyric acid

analytical standard

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About This Item

Formule empirique (notation de Hill):
C4H8O3
Numéro CAS:
Poids moléculaire :
104.10
Numéro Beilstein :
1720568
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107

Qualité

analytical standard

Pureté

≥97.0% (GC)

Durée de conservation

limited shelf life, expiry date on the label

Pf

49-50 °C (lit.)

Application(s)

clinical testing

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

C[C@@H](O)CC(O)=O

InChI

1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1

Clé InChI

WHBMMWSBFZVSSR-GSVOUGTGSA-N

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Description générale

(R)-3-Hydroxybutyric acid, a monomer of the polymer polyhydroxybutyrate (PHB), is widely used as a nutrition source and a precursor for vitamins, antibiotics and pheromones. Its potential as a protective agent against neuronal death is investigated.

Application

2(R)-3-Hydroxybutyric acid may be used as an analytical reference standard for the quantification of the analyte in urine samples using achiral dual-capillary column gas chromatography. It may also be used as a standard in the production of enantiopure (R)-3-HB using non-conventional yeast A. adeninivorans as a production host and glucose as a carbon source. The purity is determined using gas chromatography-mass spectrometric analysis (GC-MS).

Produits recommandés

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Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Production of (R)-3-hydroxybutyric acid by Arxula adeninivorans
Biernack M, et al.
AMB Express, 7(1), 4-4 (2017)
Severe child form of primary hyperoxaluria type 2-a case report revealing consequence of GRHPR deficiency on metabolism
Konkolova J, et al.
BMC Medical Genetics, 18(1), 59-59 (2017)
K R Ki et al.
Journal of chromatography. A, 891(2), 257-266 (2000-10-24)
The simultaneous enantiomeric separation of 30 racemic acids including 24 hydroxy acids in a single analysis is described for the determination of their absolute configurations. It involves the conversion of each enantiomer into diastereomeric O-trifluoroacetylated (-)-menthyl ester for the direct

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