27301

Salicylic acid

meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

• Synonyme(s) : 2-Hydroxybenzoic acid
• Formule linéaire : 2^-(HO)C₆H₄CO₂H
• Numéro CAS: 69-72-7
• Poids moléculaire : 138.12
• Beilstein: 774890
• Numéro CE : 200-712-3
• Numéro MDL: MFCD00002439
• Code UNSPSC : 12352100
• ID de substance PubChem : 24856524
• Nomenclature NACRES : NA.21

Propriétés

• Densité de vapeur: 4.8 (vs air)
• Niveau de qualité: 200
• Pression de vapeur: 1 mmHg ( 114 °C)
• Essai: 99.5-100.5% (calc. to the dried substance)
• Qualité: meets analytical specification of Ph. Eur., BP, USP
• Impuretés: residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤0.2% related subst. (HPLC)
• Résidus de calcination: ≤0.05% (as SO₄)
• Perte: ≤0.3% loss on drying
• pb: 211 °C (lit.)
• Pf: 158-161 °C (lit.); 158-161 °C
• Traces d'anions: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤200 mg/kg
• Adéquation: complies for appearance of solution; complies for identity
• Application(s): pharmaceutical (small molecule)
• Groupe fonctionnel: carboxylic acid
• Chaîne SMILES: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• Clé InChI: YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Informations sur le gène: human ... ALB(213) , PTPN1(5770)

Description

Application

• Salinity stress management in agriculture: A study demonstrated the application of salicylic acid in ameliorating salinity stress in barley, revealing its potential to enhance crop resilience to saline environments, thereby contributing to sustainable agricultural practices (Hanif et al., 2024).
• Enhanced pharmaceutical gel performance: Research on nitrocellulose for prolonged permeation of Levofloxacin HCl-Salicylic Acid In Situ gel emphasized its utility in enhancing drug delivery systems, particularly in treating bacterial infections with improved efficacy (Khaing et al., 2024).
• Biotechnological production of withanolides: Salicylic acid was applied as an elicitor in the hairy root culture of Withania somnifera, significantly boosting the production of withanolides and phenolic acids, vital for pharmaceutical applications due to their therapeutic properties (Halder and Ghosh, 2024).

Informations sur la sécurité

• Pictogrammes: GHS08,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302,H318,H361d
• Conseils de prudence: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 314.6 °F - closed cup
• Point d'éclair (°C): 157 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves