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MABF1077Z

Sigma-Aldrich

Rat IgG2a Negative Control, clone 2A3, Azide Free Antibody

clone 2A3, from rat, purified by affinity chromatography

Synonyme(s) :

Immunoglobulin G2a, IgG2a

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.42

Source biologique

rat

Niveau de qualité

Forme d'anticorps

affinity isolated antibody

Clone

2A3, monoclonal

Produit purifié par

affinity chromatography

Technique(s)

flow cytometry: suitable

Isotype

IgG2a

Modification post-traductionnelle de la cible

unmodified

Description générale

The 2A3 immunoglobulin is useful as an isotype-matched control. The 2A3 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2a antibodies.

Application

This rat monoclonal Rat IgG2a Negative Control, clone 2A3, Azide Free, Cat. No. MABF1077Z is validated for use in Flow Cytometry.

Forme physique

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, pH7.2. This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography.

Autres remarques

Concentration: Please refer to lot specific datasheet.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Brian J Kwee et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(35) (2021-08-28)
Mesenchymal stromal cells (MSCs) are increasingly combined with biomaterials to enhance their therapeutic properties, including their immunosuppressive function. However, clinical trials utilizing MSCs with or without biomaterials have shown limited success, potentially due to their functional heterogeneity across different donors
Ashley M Campbell et al.
PLoS pathogens, 18(1), e1010235-e1010235 (2022-01-11)
The Epstein-Barr virus (EBV) BGLF2 protein is a tegument protein with multiple effects on the cellular environment, including induction of SUMOylation of cellular proteins. Using affinity-purification coupled to mass-spectrometry, we identified the miRNA-Induced Silencing Complex (RISC), essential for miRNA function
Tiffany R Frey et al.
Frontiers in microbiology, 12, 708404-708404 (2021-08-27)
Human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) persist as life-long infections alternating between latency and lytic replication. Human endogenous retroviruses (HERVs), via integration into the host genome, represent genetic remnants of ancient retroviral infections. Both show similar
Eric M Burton et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(3), 1722-1730 (2020-01-11)
Viruses activate inflammasomes but then subvert resulting inflammatory responses to avoid elimination. We asked whether viruses could instead use such activated or primed inflammasomes to directly aid their propagation and spread. Since herpesviruses are experts at coopting cellular functions, we

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