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MAB979

Sigma-Aldrich

Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D

ascites fluid, clone 422-8D-4C-4D, Chemicon®

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

ascites fluid

Clone

422-8D-4C-4D, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunofluorescence: suitable

Isotype

IgG1

Conditions d'expédition

wet ice

Spécificité

Reacts with Enterovirus 71. Neutralizes enterovirus 71 BrCr strain at a titer of less than 1:14.

Immunogène

Epitope: cross-reacts with Coxsackie A16

Application

Indirect immunofluorescence at 1:1,000.

(Also cross-reacts with Coxsackie A16).

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D is validated for use in IF for the detection of Enterovirus 71.

Forme physique

Ascites fluid containing no preservatives.
Unpurified

Stockage et stabilité

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
Enterovirus Control Slides, Catalogue Number 5066

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Ming-Te Yeh et al.
PloS one, 6(11), e27082-e27082 (2011-11-10)
Enterovirus 71 (EV71) has emerged as a neuroinvasive virus responsible for several large outbreaks in the Asia-Pacific region while virulence determinant remains unexplored. In this report, we investigated increased virulence of unadapted EV71 clinical isolate 237 as compared with isolate
Combining multiplex reverse transcription-PCR and a diagnostic microarray to detect and differentiate enterovirus 71 and coxsackievirus A16.
Chen, Tsan-Chi, et al.
Journal of Clinical Microbiology, 44, 2212-2219 (2006)
Elizabeth A Caine et al.
Journal of virology, 90(19), 8592-8604 (2016-07-22)
Hand, foot, and mouth disease (HFMD) has spread throughout the Asia-Pacific region, affecting millions of young children, who develop symptoms ranging from painful blisters around their mouths and hands to neurological complications. Many members of the genus Enterovirus (family Picornaviridae)
Rei-Lin Kuo et al.
PloS one, 8(5), e63431-e63431 (2013-05-08)
Induction of type-I interferons (IFNs), IFN-α/β, is crucial to innate immunity against RNA virus infection. Cytoplasmic retinoic acid-inducible gene I (RIG-I)-like receptors, including RIG-I and melanoma differentiation-associated gene 5 (MDA5), are critical pathogen sensors for activation of type-I IFN expression
Immunological and biochemical characterization of coxsackie virus A16 viral particles.
Chong, P; Guo, MS; Lin, FH; Hsiao, KN; Weng, SY; Chou, AH; Wang, JR; Hsieh, SY; Su, IJ; Liu, CC
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