19-143
PD 98059
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About This Item
Code UNSPSC :
12352202
eCl@ss :
32160405
Nomenclature NACRES :
NA.41
Produits recommandés
Forme
solid
Niveau de qualité
Fabricant/nom de marque
Upstate®
Technique(s)
activity assay: suitable (kinase)
Conditions d'expédition
wet ice
Application
Potent, selective and cell-permeable inhibitor of MAPK kinase, MAPK/ERK, or MEKK.
Actions biochimiques/physiologiques
Inhibitor Type: Kinase
Forme physique
C16H13NO3
Stockage et stabilité
2 years at -20°C
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
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The Journal of biological chemistry, 270(46), 27489-27494 (1995-11-17)
PD 098059 has been shown previously to inhibit the dephosphorylated form of mitogen-activated protein kinase kinase-1 (MAPKK1) and a mutant MAPKK1(S217E,S221E), which has low levels of constitutive activity (Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J., and
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