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880400C

Avanti

16:0 PEG350 PE

Avanti Research™ - A Croda Brand 880400C

Synonyme(s) :

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] (ammonium salt)

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About This Item

Numéro CAS:
474922-84-4
Code UNSPSC :
12352211

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (880400C-25mg)
pkg of 2 × 4 mL (880400C-200mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 880400C

Concentration

10 mg/mL (880400C-25mg)
25 mg/mL (880400C-200mg)

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

Description générale

16:0 PEG350 PE is a polyethylene glycol (PEG) conjugated phospholipid. It is a biopolymer with a molecular weight of 1075.4 Da.[1]

Application

16:0 PEG350 PE is suitable for use in the preparation of Pdots and to differentiate based on shell′s composition.[2] It might also be used in membrane preparation to study water dynamics.[1]

Actions biochimiques/physiologiques

Polyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation[3] and are used as drug carriers.[4] PEGylated lipids maintain the stereochemistry of liposomes. The formation of mixed micelles is supported by the use of highly concentrated PEG-lipids.[5]

Conditionnement

5 mL Clear Glass Sealed Ampule (880400C-200mg)
5 mL Clear Glass Sealed Ampule (880400C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organes cibles

Liver,Kidney, Respiratory system

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash

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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Eduardo M Clop et al.
The journal of physical chemistry. B, 118(23), 6150-6158 (2014-05-09)
The present work was aimed at studying the molecular dynamics at different levels of model membranes having a simulated glycoclix, with focus on the molecular crowding conditions at the lipid-water interfacial region. Thus, binary mixtures of dipalmitoylphosphatidylcholine (dpPC) and a
Pdots nanoparticles load photosensitizers and enhance efficiently their photodynamic effect by FRET
Haimov E, et al.
Royal Society of Chemistry Advances, 5(24), 18482-18491 (2015)
Sirkku Hanski et al.
Biomacromolecules, 11(12), 3440-3447 (2010-10-27)
We report on highly ordered oblique self-assemblies in ionic complexes of PEGylated triple-tail lipids and cationic polypeptides, as directed by side-chain crystallization, demonstrating also reversible oblique-to-hexagonal order-order transitions upon melting of the side chains. This is achieved in bulk by
Maria C Sandström et al.
Langmuir : the ACS journal of surfaces and colloids, 23(8), 4192-4198 (2007-03-09)
Polyethylene glycol (PEG)-conjugated lipids are commonly employed for steric stabilization of liposomes. When added in high concentrations PEG-lipids induce formation of mixed micelles, and depending on the lipid composition of the sample, these may adapt either a discoidal or a
G F Peacock et al.
Drug delivery, 10(1), 29-34 (2003-01-30)
A new cholesterol-carborane conjugate (BCH) has been synthesized as a potential targeting agent for boron neutron capture therapy (BNCT) of cancers. The compound is extremely water insoluble and was formulated in two liposomal formulations to determine if the compound could

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