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850338P

Avanti

MAPCHO™-14

n-tetradecylphosphocholine, powder

Synonyme(s) :

TPC; Fos-Choline-14; FOS14; FC-14

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About This Item

Formule empirique (notation de Hill):
C19H42NO4P
Numéro CAS:
77733-28-9
Poids moléculaire :
379.51
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 1 g (850338P-1g)
pkg of 1 × 10 g (850338P-10g)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 850338P

Conditions d'expédition

dry ice

Température de stockage

−20°C

InChI

1S/C19H42NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-23-25(21,22)24-19-17-20(2,3)4/h5-19H2,1-4H3

Clé InChI

BETUMLXGYDBOLV-UHFFFAOYSA-N

Description générale

MAPCHO™-14 is a fos-choline-based zwitterionic detergent.
Tetradecylphosphocholine is a structural analog of myristoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification. It has been used as a helper lipid for in vitro and in vivo gene transfer, and it has been shown to have some anticancer activity.

Application

MAPCHO™-14 has been used as a supplement in extraction buffer (RIPA buffer).

Actions biochimiques/physiologiques

Fos-choline-14 (N-tetradecylphosphocholine) is mainly used for solubilization and purification of proteins.

Conditionnement

20 mL Clear Glass Screw Cap Vial (850338P-1g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850338P-10g)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line
Cook BL, et al.
Testing, 3(8), e2920-e2920 (2008)
Brian L Cook et al.
PloS one, 3(8), e2920-e2920 (2008-08-07)
In order to begin to study the structural and functional mechanisms of olfactory receptors, methods for milligram-scale purification are required. Here we demonstrate the production and expression of a synthetically engineered human olfactory receptor hOR17-4 gene in a stable tetracycline-inducible
Pernille M Christensen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(6), 2351-2359 (2016-03-10)
Apolipoprotein M (ApoM) transports sphingosine-1-phosphate (S1P) in plasma, and ApoM-deficient mice (Apom(-/-)) have ∼50% reduced plasma S1P levels. There are 5 known S1P receptors, and S1P induces adherens junction formation between endothelial cells through the S1P1 receptor, which in turn
Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1
Christensen PM, et al.
Faseb Journal, 30(6), 2351-2359 (2016)
Julia Koehler et al.
Biochemistry, 49(33), 7089-7099 (2010-07-30)
There has been a renewal of interest in interactions of membrane proteins with detergents and lipids, sparked both by recent results that illuminate the structural details of these interactions and also by the realization that some experimental membrane protein structures
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