638013

4-Diphenylphosphanylbenzoic acid, 2-(trimethylsilyl)ethyl ester solution

0.5 M in THF

• Formule empirique (notation de Hill): C₂₄H₂₇O₂PSi
• Numéro CAS: 566190-45-2
• Poids moléculaire : 406.53
• Numéro MDL: MFCD07369722
• Code UNSPSC : 12352108
• ID de substance PubChem : 24882904

Propriétés

• Capacité de réaction: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• Pertinence de la réaction: reagent type: ligand
• Concentration: 0.5 M in THF
• Densité: 0.925 g/mL at 25 °C
• Groupe fonctionnel: phosphine
• Chaîne SMILES: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• Clé InChI: QTYUNPJLGFKKRV-UHFFFAOYSA-N

Description

Application

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

Informations sur la sécurité

• Pictogrammes: GHS02,GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H319,H335,H351
• Conseils de prudence: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Classification des risques: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Risques supp: EUH019
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): -4.0 °F - closed cup
• Point d'éclair (°C): -20 °C - closed cup