42358

Dioctadecylamine

≥99.0% (NT)

• Synonyme(s) : DODA, Distearylamine
• Formule linéaire : [CH₃(CH₂)₁₇]₂NH
• Numéro CAS: 112-99-2
• Poids moléculaire : 521.99
• Beilstein: 1801688
• Numéro CE : 204-020-2
• Numéro MDL: MFCD00048494
• Code UNSPSC : 12352100
• ID de substance PubChem : 57650109
• Nomenclature NACRES : NA.22

Propriétés

• Essai: ≥99.0% (NT)
• Pf: 71-73 °C
• Solubilité: water: soluble(lit.)
• Groupe fonctionnel: amine
• Chaîne SMILES: CCCCCCCCCCCCCCCCCCNCCCCCCCCCCCCCCCCCC
• InChI: 1S/C36H75N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37H,3-36H2,1-2H3
• Clé InChI: HKUFIYBZNQSHQS-UHFFFAOYSA-N

Description

Description générale

Dioctadecylamine (DODA), a secondary amine, is a fatty amine derivative. Its biodegradation potential has been assessed.[1] It has been observed that in aqueous medium DODA self organizes into plate like structures. Its partial charge distribution as a function of its conformation has been analyzed.[2] The phase diagram of dioctadecylamine Langmuir monolayers has been determined and investigations show it does not form a monolayer above pH 3.9.[3] DODA has been utilized in forming liposomes, cationic lipids or lipid chelating agents.[4]

Application

Dioctadecylamine (DODA) is suitable reagent used in the synthesis of the following:

• Dioctadecylamine-BCN (bicyclo[6.1.0]nonyne) conjugate.[5]
• Lipid derivatives of bisethylnorspermine (BSP).[6]
• Functional VP (N-vinylpyrrolidone ) polymers.[7]

It may be used in the following studies:

• As a reactant in the synthesis of 4,4′-azobis(4-cyano-N,N-dioctadecyl)pentanamide (DODA-501) by reacting with disuccinimidyl 4,4′-azobis(4-cyanovalerate).[8]
• As a reagent in the synthesis of dioctadecyl heptapeptides.[9]
• As a phase transfer and stabilizer agent for gold nanoparticles (AuNPs) in non-polar solvent.[10]

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves