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PAMAM dendrimer

ethylenediamine core, generation 0.0 solution, 20 wt. % in methanol

Synonyme(s) :

Poly(amidoamine)

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Disponible pour expédition le14 avril 2025Détails


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5 G
135,00 $
25 G
593,00 $

About This Item

Formule linéaire :
NH2(CH2)2NH2]:(G=0);dendri PAMAM(NH2)4
Numéro CAS:
Poids moléculaire :
516.68
Numéro MDL:
Code UNSPSC :
12162002
ID de substance PubChem :
Nomenclature NACRES :
NA.23

135,00 $


Disponible pour expédition le14 avril 2025Détails


Devis pour commande en gros

Description

amino surface groups

Forme

liquid

Poids mol.

generation 0.0

Caractéristiques

core type ethylenediamine core (2-carbon core)

Concentration

20 wt. % in methanol

Nb de groupes de surface

4

Indice de réfraction

n20/D 1.364

pb

64.7 °C

Densité

0.854 g/mL at 25 °C

Température de stockage

2-8°C

Chaîne SMILES 

NCCNC(=O)CCN(CCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN

InChI

1S/C22H48N10O4/c23-5-9-27-19(33)1-13-31(14-2-20(34)28-10-6-24)17-18-32(15-3-21(35)29-11-7-25)16-4-22(36)30-12-8-26/h1-18,23-26H2,(H,27,33)(H,28,34)(H,29,35)(H,30,36)

Clé InChI

SENLDUJVTGGYIH-UHFFFAOYSA-N

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Description générale

PAMAM dendrimer is a poly(amidoamine) that is categorized under the class of dendritic polymers, which can be prepared by a two-step reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular branched upon branched pattern. PAMAM is majorly used as a high capacity chelating agent.[1][2]

Application

PAMAM dendrimer belongs to the family of dendrimers, which can be used in biomedical and drug delivery applications.[3][4][5]

Forme physique

Contains 4 surface primary amino groups

Informations légales

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup


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Certificats d'analyse (COA)

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality
Majoros I, et al.
Biomacromolecules, 7(2), 572-579 (2006)
Poly (ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery
Luo D, et al.
Macromolecules, 35(9), 3456-3462 (2002)
Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
Esfand R and Tomalia DA
Drug Discovery Today, 6(8), 427-436 (2001)
Dendritic chelating agents. 1. Cu (II) binding to ethylene diamine core poly (amidoamine) dendrimers in aqueous solutions
Diallo MS, et al.
Langmuir, 20(7), 2640-2651 (2004)
Dendrimer enhanced ultrafiltration. 1. Recovery of Cu (II) from aqueous solutions using PAMAM dendrimers with ethylene diamine core and terminal NH2 groups
Diallo MS, et al.
Environmental Science & Technology, 39(5), 1366-1377 (2005)

Articles

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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