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Key Documents

SML3065

Sigma-Aldrich

PFI-6

≥98% (HPLC)

Synonym(s):

(R)-N-(2,3-Dihydro-1H-inden-1-yl)-5-(4-(dimethylcarbamoyl)-3-hydroxyphenyl)isoxazole-3-carboxamide

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5 MG
$129.00
25 MG
$517.00

$129.00


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5 MG
$129.00
25 MG
$517.00

About This Item

Empirical Formula (Hill Notation):
C22H21N3O4
CAS Number:
Molecular Weight:
391.42
UNSPSC Code:
12352200
NACRES:
NA.77

$129.00


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Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

PFI-6 is a cell penetrant, potent and selective inhibitor of MLLT1/3. PFI-6 binds into the YEATS domain of MLLT1/3.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Questions

  1. What is the IC50 of the selective inhibitor PFI-6 (SML3065-25MG)?

    1 answer
    1. The IC50 of SML3065-25MG is 0.14 µM against MLLT1 and 0.16 µM against MLLT2.

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