RAB0135
Human NAP-2 / CXCL7 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.5 pg/mL
standard curve range: 4.1-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PPBP(5473)
General description
Platelet-derived chemokine (C-X-C motif) ligand 7 (CXCL7), also known as neutrophil-activating protein-2 (NAP-2), is a member of a subset of seven chemokines. The protein is produced in platelets and its structure contains an N-terminal glutamate-leucine-arginine (ELR) motif. It acts as a ligand for the CXC chemokine receptor 2 (CXCR2). NAP-2 facilitates the migration of bone marrow mesenchymal stem cells (MSCs) to the injury site. In addition, it also aids in monocyte recruitment during atherogenesis. The Human NAP-2 enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human NAP-2 in serum, plasma, cell culture supernatants, and urine.
The Human NAP-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human NAP-2 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human NAP2
Application
Human NAP-2 / CXCL7 ELISA Kit has been used in enzyme-linked immunosorbent assay to quantitatively measure NAP-2/CXCL7 in serum samples of chronic myelomonocytic leukemia (CMML) patients.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
For research use only. Not for use in diagnostic procedures.
Please type the word sample in the text box provided for lot number.
For research use only. Not for use in diagnostic procedures.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Certificates of Analysis (COA)
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Thomas Baltus et al.
Journal of leukocyte biology, 78(2), 435-441 (2005-05-19)
Platelet-derived chemokines, such as regulated on activation, normal T expressed and secreted (RANTES; CC chemokine ligand 5), platelet factor 4 [PF4; CXC chemokine ligand 4 (CXCL4)], and epithelial neutrophil-activating protein 78 (ENA-78; CXCL5), or precursors, such as beta-thromboglobulin, which can
Catarina R Almeida et al.
Stem cell reports, 6(4), 466-473 (2016-04-08)
Strategies for improved homing of mesenchymal stem cells (MSCs) to a place of injury are being sought and it has been shown that natural killer (NK) cells can stimulate MSC recruitment. Here, we studied the chemokines behind this recruitment. Assays
Wei Jiang et al.
Experimental and therapeutic medicine, 19(4), 2449-2456 (2020-04-08)
Overuse and misuse of antibiotics leads to antibiotic resistance which has become a significant public health concern. Klebsiella pneumoniae is the most common pathogenic bacteria underlying nosocomial infections due to the expression of virulence factors and occurrence of antibiotic resistance.
Aaron J Brown et al.
Frontiers in immunology, 8, 1248-1248 (2017-10-19)
Platelet-derived chemokine CXCL7 (also known as NAP-2) plays a crucial role in orchestrating neutrophil recruitment in response to vascular injury. CXCL7 exerts its function by activating the CXC chemokine receptor 2 (CXCR2) receptor and binding sulfated glycosaminoglycans (GAGs) that regulate
Qian Guo et al.
Oncology reports, 37(2), 1114-1122 (2016-12-14)
CXCL7 is an important chemoattractant cytokine, which signals through binding to its receptor CXCR2. Recent studies have demonstrated that the CXCL7/CXCR2 signaling plays a promoting role in several common malignancies, including lung, renal, colon, and breast cancer. However, the regulatory
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