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L2136

Sigma-Aldrich

Lauric acid N,N-dimethylamide

~95%

Synonym(s):

N,N-Dimethyldodecanamide, N,N-Dimethyllauramide

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About This Item

Empirical Formula (Hill Notation):
C14H29NO
CAS Number:
Molecular Weight:
227.39
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:

Assay

~95%

form

liquid

density

0.87 g/mL at 25 °C (lit.)

functional group

amide

shipped in

ambient

storage temp.

room temp

SMILES string

CCCCCCCCCCCC(=O)N(C)C

InChI

1S/C14H29NO/c1-4-5-6-7-8-9-10-11-12-13-14(16)15(2)3/h4-13H2,1-3H3

InChI key

BDYUSDIJIDGWCY-UHFFFAOYSA-N

Application

Dermal penetration enhancer; facilitates transport of solutes through the skin.

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B B Michniak et al.
Journal of pharmaceutical sciences, 82(2), 214-219 (1993-02-01)
A series of novel dermal penetration enhancers, esters and amides of clofibric acid, was synthesized. The permeation parameters and skin retention of two steroids (hydrocortisone-21-acetate and betamethasone-17-valerate) in propylene glycol were studied with athymic nude mouse skin by in vitro
Kuo-Yen Huang et al.
EMBO molecular medicine, 13(1), e12828-e12828 (2020-11-08)
To circumvent the devastating pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, a humanized decoy antibody (ACE2-Fc fusion protein) was designed to target the interaction between viral spike protein and its cellular receptor, angiotensin-converting enzyme 2 (ACE2).

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