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D0100000

Dapsone

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Aminophenyl sulfone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, Bis(4-aminophenyl) sulfone, DDS, Dapsone

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100 MG
$169.00

$169.00

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100 MG
$169.00

About This Item

Linear Formula:
(H2NC6H4)2SO2
CAS Number:
80-08-0
Molecular Weight:
248.30
Beilstein:
788055
MDL number:
MFCD00007887
UNSPSC Code:
41116107
PubChem Substance ID:
329798581
NACRES:
NA.24

$169.00

Please contact Customer Service for Availability
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grade

pharmaceutical primary standard

Agency

EP Reference Standard

API family

dapsone

manufacturer/tradename

EDQM

mp

175-177 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2

InChI

1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChI key

MQJKPEGWNLWLTK-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dapsone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Description
Pricing

Signal Word

Danger

Hazard Statements

H302,H360F,H371,H373,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 1B - STOT RE 2 - STOT SE 2

Target Organs

Blood, Blood,spleen,Liver

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Leon H Kircik
Journal of drugs in dermatology : JDD, 9(6), 667-671 (2010-07-22)
Data continue to establish the role of inflammation, not only in the pathogenesis of acne but also in the development of its most devastating sequelum, scarring. Although topical therapy is preferred by most acne patients and the physicians who treat
Evan W Piette et al.
Dermatologic clinics, 29(4), 561-564 (2011-09-20)
Dapsone is used in the treatment of autoimmune bullous diseases (AIBD), a group of disorders resulting from autoimmunity directed against basement membrane and/or intercellular adhesion molecules on cutaneous and mucosal surfaces. This review summarizes the limited published data evaluating dapsone
Evan W Piette et al.
Immunology and allergy clinics of North America, 32(2), 317-322 (2012-05-09)
Dapsone is used in the treatment of autoimmune bullous diseases (AIBD), a group of disorders resulting from autoimmunity directed against basement membrane and/or intercellular adhesion molecules on cutaneous and mucosal surfaces. This review summarizes the limited published data evaluating dapsone
James A Barclay et al.
The Annals of pharmacotherapy, 45(9), 1103-1115 (2011-08-20)
To present a comprehensive review of dapsone-induced methemoglobinemia and its management. Literature retrieval was accessed through MEDLINE (1966-March 2011), Cochrane Library, and EMBASE, using the terms dapsone and methemoglobinemia. All case reports, small case series, and randomized controlled trials published
Jennifer Tan et al.
Journal of cutaneous medicine and surgery, 10(2), 92-95 (2007-01-24)
Mesotherapy is a procedure involving the injection of substances into the dermis and subcutaneous tissue. Used in Europe for decades in the treatment of various medical conditions and cosmetic fat dissolution, the technique only recently became widely available in the
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