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Sigma-Aldrich

Cathepsin B Substrate III, Fluorogenic

≥95% (HPLC), lyophilized solid, Cathepsin B inhibitor, Calbiochem®

Synonym(s):

Cathepsin B Substrate III, Fluorogenic, Z-RR-AMC, 2HCl

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About This Item

Empirical Formula (Hill Notation):
C30H39N9O6 · 2HCl
Molecular Weight:
694.61
UNSPSC Code:
51111800
NACRES:
NA.77

product name

Cathepsin B Substrate III, Fluorogenic, Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.

Quality Level

100

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

white

solubility

DMSO: 5 mg/mL
water: soluble

fluorescence

λex 360-380 nm
λem 430-460 nm

shipped in

ambient

storage temp.

−20°C

General description

Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity (excitation maximum: 380 nm; emission maximum: 460 nm).
Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Arg-Arg-AMC, 2HCl

Other Notes

Hiwasa, T., et al. 1987. FEBS Lett.211, 23.
Manson, R.W., et al. 1985. Biochem. J.226, 233.
Tanaka, M., et al. 1985. Life Sci. 36, 1217.
Docherty, K., et al. 1984. J. Biol. Chem.259, 6041.
Barrett, A.J., and Kirschke, H. 1981. Methods Enzymol.80, 535.
Barrett, A.J. 1980. Biochem. J.187, 909.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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