178461

Apolipoprotein C-III, Human Plasma, Very Low-Density Lipoprotein

Native Apolipoprotein C-III from human plasma found in VLDL and chylomicrons. Involved in triglyceride uptake by cells. Inhibits lipoprotein lipase and uptake of lipoprotein remnants by the liver.

• Synonym(s): Apo C-III
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (SDS-PAGE)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

Native apolipoprotein C-III from human plasma. Major protein of VLDL and chylomicrons. Involved in the uptake of triglycerides by cells. May inhibit the activation of lipoprotein lipase by Apo C-II. Present in normal plasma at 80-150 µg/ml.

Native apolipoprotein C-III from human plasma. Present in normal plasma at 80-150 µg/ml. Major protein of VLDL and chylomicrons. Involved in the uptake of triglycerides by cells. May inhibit the activation of lipoprotein lipase by Apo C-II.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 10 mM NH₄HCO₃, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Bonnet, E., et al. 2001. J. Clin. Endocrinol. Metab.86, 296.
Hasse, R., et al. 1998. Electrophoresis 9, 569.
Catapano, A.L., et al. 1978. J. Lipid Res. 19, 1047.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable