Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

759317

Sigma-Aldrich

4,4,4,4′,4′,4′-Hexafluoro-DL-valine

97%

Synonym(s):

2-Amino-4,4,4-trifluoro-3-(trifluoromethyl)butyric acid, 4,4,4,5,5,5-Hexafluoro-DL-valine

Sign Into View Organizational & Contract Pricing

Select a Size

250 MG
$94.00

$94.00

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(1)

Select a Size

Change View
250 MG
$94.00

About This Item

Linear Formula:
(CF3)2CHCH(NH2)COOH
CAS Number:
16063-80-2
Molecular Weight:
225.09
Beilstein:
2416649
EC Number:
240-207-5
MDL number:
MFCD00014349
UNSPSC Code:
12352100
PubChem Substance ID:
329766772
NACRES:
NA.22

$94.00

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

97%

form

crystals

mp

196-217 °C

application(s)

peptide synthesis

functional group

amine
carboxylic acid
fluoro

SMILES string

NC(C(C(F)(F)F)C(F)(F)F)C(O)=O

InChI

1S/C5H5F6NO2/c6-4(7,8)2(5(9,10)11)1(12)3(13)14/h1-2H,12H2,(H,13,14)

InChI key

KRNSHCKTGFAMPQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBM1254

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

W H Vine et al.
Journal of medicinal chemistry, 24(9), 1043-1047 (1981-09-01)
Gamma, gammma, gammma, gammma', gamma', gammma'-Hexafluorovaline and derivatives have been prepared and incorporated into angiotensin II by fragment condensation and solid-phase peptide synthesis. Hexafluorovaline derivatives showed general resistance toward various enzymatic digestions and the tendency to racemize extensively upon carboxyl
K H Hsieh et al.
Journal of medicinal chemistry, 30(6), 1097-1100 (1987-06-01)
An improved synthesis of hexafluorovaline (Hfv) derivatives, i.e., DL-Hfv-OBzl and Boc-DL-Hfv, is described. Incorporation of hexafluorovaline into angiotensin resulted in [Sar1,Hfv8]AII and [Sar1,D-Hfv8]AII. At the nanogram/milliliter dose range, the L congener was 20-100 times more active as either angiotensin agonist

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service