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683728

Sigma-Aldrich

6-Chloro[1,3]dioxolo[4,5-g]quinoline-7-carboxaldehyde

97%

Synonym(s):

2-Chloro-6,7-methylenedioxy-3-quinolinecarboxaldehyde

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About This Item

Empirical Formula (Hill Notation):
C11H6ClNO3
CAS Number:
Molecular Weight:
235.62
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

powder

mp

230-234 °C

SMILES string

Clc1nc2cc3OCOc3cc2cc1C=O

InChI

1S/C11H6ClNO3/c12-11-7(4-14)1-6-2-9-10(16-5-15-9)3-8(6)13-11/h1-4H,5H2

InChI key

BFMGNLHCLPBIHN-UHFFFAOYSA-N

Application

Starter in the synthesis of the quinoline based natural products

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mark A Elban et al.
Organic letters, 8(16), 3513-3516 (2006-07-28)
[reaction: see text] 10,11-Methylenedioxy-14-azacamptothecin, a potent analogue of the antitumor agent camptothecin (CPT), has been prepared via a key condensation between AB and DE ring precursors. The biological testing of this compound validated a strategy for modulation of the off-rate

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