683728
6-Chloro[1,3]dioxolo[4,5-g]quinoline-7-carboxaldehyde
97%
Synonym(s):
2-Chloro-6,7-methylenedioxy-3-quinolinecarboxaldehyde
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About This Item
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Assay
97%
form
powder
mp
230-234 °C
SMILES string
Clc1nc2cc3OCOc3cc2cc1C=O
InChI
1S/C11H6ClNO3/c12-11-7(4-14)1-6-2-9-10(16-5-15-9)3-8(6)13-11/h1-4H,5H2
InChI key
BFMGNLHCLPBIHN-UHFFFAOYSA-N
Application
Starter in the synthesis of the quinoline based natural products
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Organic letters, 8(16), 3513-3516 (2006-07-28)
[reaction: see text] 10,11-Methylenedioxy-14-azacamptothecin, a potent analogue of the antitumor agent camptothecin (CPT), has been prepared via a key condensation between AB and DE ring precursors. The biological testing of this compound validated a strategy for modulation of the off-rate
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