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532355

Sigma-Aldrich

(R)-(+)-1,2-Epoxybutane

98%

Synonym(s):

(2R)-Ethyloxirane

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
3760-95-0
Molecular Weight:
72.11
MDL number:
MFCD02683444
UNSPSC Code:
12352005
PubChem Substance ID:
24877882
NACRES:
NA.22

Assay

98%

optical activity

[α]20/D 10°, neat

refractive index

n20/D 1.386 (lit.)

bp

63 °C (lit.)

density

0.837 g/mL at 25 °C (lit.)

SMILES string

CC[C@@H]1CO1

InChI

1S/C4H8O/c1-2-4-3-5-4/h4H,2-3H2,1H3/t4-/m1/s1

InChI key

RBACIKXCRWGCBB-SCSAIBSYSA-N

Related Categories

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

10.0 °F - closed cup

Flash Point(C)

-12.2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A Ohnishi et al.
Environmental research, 60(2), 242-247 (1993-02-01)
Axonal neuropathy occurs due to occupational ethylene oxide (EtO) exposure. The experimental model of human EtO neuropathy was established. In addition, the neurotoxic effects of propylene oxide (PpO) and butylene oxide (BtO) were demonstrated in rats. Although no human neuropathy
Zhengyuan Zhou et al.
International journal of pharmaceutics, 354(1-2), 82-87 (2007-12-08)
Ethylene oxide and 1,2-butylene oxide were sequentially polymerised to form the diblock copolymer E13B10 (E=oxyethylene, B=oxybutylene, subscripts denote number-average block lengths in repeat units). Dynamic and static light scattering over the temperature range 10-30 degrees C demonstrated a transition from
D Weinstein et al.
Environmental mutagenesis, 3(1), 1-9 (1981-01-01)
Based on the findings of Nagao et al [1978] that phenacetin is negative in the standard Ames test with Aroclor induced rat S-9 and positive with hamster S-9, the test was performed with a mixture of rat/hamster S-9. Phenacetin was
D Henschler et al.
Journal of cancer research and clinical oncology, 107(3), 149-156 (1984-01-01)
Previous analytical studies of industrial samples of trichloroethylene (TRI) have revealed the presence of mutagenic and carcinogenic epoxides which, it was proposed, might be responsible for the carcinogenicity of such samples, as demonstrated with mice in other laboratories. To test
J K Dunnick et al.
Toxicology, 50(1), 69-82 (1988-06-01)
1,2-Epoxybutane, a short-chain epoxide used as a stabilizer in chlorinated hydrocarbon solvents, was administered by inhalation exposure as a vapor 6 h/day, 5 day/week, for 24 months at exposure concentrations of 0, 200 or 400 ppm to F344/N rats and
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