C2278

CAPSO

≥99% anhydrous basis (titration)

• Synonym(s): 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, CAPSO Free Acid
• Empirical Formula (Hill Notation): C₉H₁₉NO₄S
• CAS Number: 73463-39-5
• Molecular Weight: 237.32
• UNSPSC Code: 12161700
• NACRES: NA.25
• PubChem Substance ID: 24892483
• MDL number: MFCD00041778
• Beilstein/REAXYS Number: 5939234

Properties

• Quality Segment: 200
• assay: ≥99% anhydrous basis (titration)
• form: crystalline powder
• pH: 2.5-4.0
• useful pH range: 8.9-10.3
• pKa (25 °C): 9.6
• solubility: water: 0.111 g/mL, clear, colorless
• application(s): diagnostic assay manufacturing
• SMILES string: OC(CNC1CCCCC1)CS(O)(=O)=O
• InChI: 1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14)
• InChI key: INEWUCPYEUEQTN-UHFFFAOYSA-N

Description

General description

CAPSO is a useful secondary standard buffer. Second dissociation constant pK₂ value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.

Application

CAPSO was used as biological buffer in the following studies:

• To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.
• Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes. I
• Preparation of planar bilayer lipid membranes.

It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)