A6981

Acamprosate calcium

≥98% (HPLC), powder

• Synonym(s): 3-(Acetylamino)-1-propanesulfonic acid calcium salt (2:1)
• Empirical Formula (Hill Notation): C₅H₁₀Ca_0.5NO₄S
• CAS Number: 77337-73-6
• Molecular Weight: 200.24
• EC Number: 278-665-3
• UNSPSC Code: 12352200
• PubChem Substance ID: 329770909
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• solubility: H₂O: >5 mg/mL
• storage temp.: room temp
• SMILES string: CC(=O)NCCCS(=O)(=O)O[Ca]OS(=O)(=O)CCCNC(C)=O
• InChI: 1S/2C5H11NO4S.Ca/c2*1-5(7)6-3-2-4-11(8,9)10;/h2*2-4H2,1H3,(H,6,7)(H,8,9,10);/q;;+2/p-2
• InChI key: BUVGWDNTAWHSKI-UHFFFAOYSA-L
• Gene Information: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444)

Description

Biochem/physiol Actions

Acamprosate calcium is a synthetic analog of γ-aminobutyric acid (GABA) and a GABAB receptor agonist. Acamprosate calcium has been used in alcohol dependence treatments and may be an effective augmentation therapy anxiety patients.

Acamprosate calcium is a GABA γ-aminobutyric acid agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves