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04434

Sigma-Aldrich

Sodium hypophosphite

puriss., meets analytical specification of BPC63, anhydrous, 98-101%

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About This Item

Linear Formula:
NaPH2O2
CAS Number:
Molecular Weight:
87.98
EC Number:
MDL number:
UNSPSC Code:
12352302
eCl@ss:
38070302
PubChem Substance ID:
NACRES:
NA.21

grade

puriss.

Assay

98-101%

form

powder or crystals

quality

meets analytical specification of BPC63

impurities

≤0.001% heavy metals (as Pb)
≤0.2% free alkali (as CaO)

loss

≤1% loss on drying, 105 °C, 2 h

solubility

water: soluble 909 g/L at 30 °C

density

1.77 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

As: ≤2 mg/kg
Fe: ≤10 mg/kg

SMILES string

[Na+].[O-][PH2]=O

InChI

1S/Na.H3O2P/c;1-3-2/h;3H2,(H,1,2)/q+1;/p-1

InChI key

SIGUVTURIMRFDD-UHFFFAOYSA-M

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General description

Sodium hypophosphite, also known as sodium phosphinate, is a sodium salt of hypophosphorous acid. It is used as a reducing agent for the reduction of metal salts to metals in an aqueous solution. It is also employed as a source of hydrogen in heterogeneous catalytic transfer reductions.

Application


  • Synthesis and characterization of chitosan-copper nanocomposites and their catalytic properties for 4-nitrophenol reduction.: This study explores the synthesis of chitosan-copper nanocomposites using sodium hypophosphite as a reducing agent. The resulting nanocomposites are characterized and their catalytic properties for the reduction of 4-nitrophenol are evaluated, demonstrating the utility of sodium hypophosphite in catalytic applications (Pang et al., 2024).

  • The Durable Chitosan Functionalization of Cellulosic Fabrics.: This research focuses on the durable functionalization of cellulosic fabrics with chitosan using sodium hypophosphite as a cross-linking agent. The study highlights the improved properties of the fabrics, showcasing sodium hypophosphite′s role in textile enhancement (Flinčec Grgac et al., 2023).

  • Hypophosphite cross-linked starch succinate/chitosan membranes as alternative for packaging and pharmaceutical application.: The study investigates the development of starch succinate/chitosan membranes cross-linked with sodium hypophosphite, proposing these materials as potential alternatives for packaging and pharmaceutical applications (Bajer, 2023).

  • Tensile Strength Improvements of Ramie Fiber Threads through Combination of Citric Acid and Sodium Hypophosphite Cross-Linking.: This research improves the tensile strength of ramie fiber threads by combining citric acid and sodium hypophosphite for cross-linking, demonstrating significant enhancements in fiber properties for industrial applications (Wulandari et al., 2023).

  • Nickel-Catalyzed Sodium Hypophosphite-Participated Direct Hydrophosphonylation of Alkyne toward H-Phosphinates.: This study demonstrates a novel nickel-catalyzed hydrophosphonylation of alkynes using sodium hypophosphite. The research showcases the efficiency of sodium hypophosphite in producing H-phosphinates, highlighting its significance in chemical synthesis (Qian et al., 2023).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Rapid synthesis of copper nanoparticles by sodium hypophosphite reduction in ethylene glycol under microwave irradiation.
Zhu H-T, et al.
Journal of Crystal Growth, 270(3), 722-728 (2004)
Reduction of carbon-carbon double bonds and hydrogenolysis by sodium hypophosphite.
Sala R, et al.
Tetrahedron Letters, 25(40), 4565-4568 (1984)
Mohammad H Eskandari et al.
Food science & nutrition, 1(5), 392-401 (2014-05-08)
Nitrite-free and low-nitrite meat-curing systems were developed to eliminate or reduce nitrite in frankfurter-type sausages. Different composite meat-curing mixtures were formulated using cochineal and paprika as natural colorants, sodium hypophosphite (SHP) as antimicrobial agent, butylated hydroxyanisole (BHA) as antioxidant and
Efficient large-scale radical deoxygenation in alcoholic solvents using sodium hypophosphite and a phase-transfer agent: application to erythromycins.
A E Graham et al.
The Journal of organic chemistry, 65(8), 2583-2585 (2000-05-02)
S Hopper et al.
The Journal of biological chemistry, 269(30), 19597-19604 (1994-07-29)
Purified FHLA, the transcriptional activator of the formate regulon from Escherichia coli, is able to efficiently stimulate transcription from the sigma 54-dependent promoters of the fdhF, hyp, and hyc transcriptional units. Expression was dependent on the presence of sigma 54

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