B3916

Boldine

analytical standard

• Synonym(s): 2,9-Dihydroxy-1,10-dimethoxyaporphine
• Empirical Formula (Hill Notation): C₁₉H₂₁NO₄
• CAS Number: 476-70-0
• Molecular Weight: 327.37
• Beilstein: 94036
• EC Number: 207-509-9
• MDL number: MFCD00135040
• UNSPSC Code: 41116107
• PubChem Substance ID: 329773223
• NACRES: NA.24

Properties

• biological source: plant (Peumus boldus molina)
• Quality Level: 100
• grade: analytical standard
• Assay: ≥98% (TLC)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤1% isopropanol
• mp: 157-164 °C
• solubility: ethanol: 50 mg/mL
• application(s): food and beverages; forensics and toxicology; veterinary
• format: neat
• storage temp.: room temp
• SMILES string: COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c-2c34)cc1O
• InChI: 1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1
• InChI key: LZJRNLRASBVRRX-ZDUSSCGKSA-N

Description

General description

Boldine is an aporphine alkaloid isolated from Boldo tree and other plant species. It is a free radical scavenger with anti-inflammatory activity while exhibiting other pharmacological effects such as antidiabetic, antiplatelet aggregation, antipyretic, antinociceptive, antiatherogenic, hepatoprotective and endothelium-protective activity.

Application

Boldine may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical preparations using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves