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Milli-Q

Biopak® Polisher

Ultrafilter for the production of pyrogen-, nuclease-, protease- and bacteria-free water at the point of dispense of Milli-Q® IQ/IX/EQ systems

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About This Item

UNSPSC Code:
41104212
eCl@ss:
33050190
NACRES:
JA.13

material

polysulfone filter

Quality Level

packaging

pkg of 1 unit

manufacturer/tradename

BioPak®

technique(s)

ELISA: suitable
PCR: suitable
cell culture | mammalian: suitable

compatibility

for use with Milli-Q® EQ 7000
for use with Milli-Q® EQ 7008
for use with Milli-Q® EQ 7016
for use with Milli-Q® IX 7003
for use with Milli-Q® IX 7005
for use with Milli-Q® IX 7010
for use with Milli-Q® IX 7015
for use with Milli-Q® IQ 7000
for use with Milli-Q® IQ 7003
for use with Milli-Q® IQ 7005
for use with Milli-Q® IQ 7010
for use with Milli-Q® IQ 7015

shipped in

ambient

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General description

The Biopak® Polisher is an ultrafiltration cartridge designed to produce water suitable for molecular biology, biochemistry and cell culture when fed with Milli-Q® purified water. It is validated for continuous use for 90 days.

Application

Biopak® Polisher ultrafiltration cartridge is suitable for use with Milli-Q® IX 7003/05/10/15, Milli-Q® IQ 7000, Milli-Q® IQ 7003/05/10/15, Milli-Q® EQ 7000 and Milli-Q® EQ 7008/16 water purification systems.. Designed for applications such as molecular biology, biochemistry and cell culture (when fed with Milli-Q® purified water), the Biopak® ultrafiltration unit removes macromolecules and larger biological structures, such as bacteria.

Biopak® Polisher is recommended for a wide range of laboratory applications where bacteria, pyrogen, nuclease and/or protease levels must be controlled.
This includes small-interfering RNA (siRNA) research, RNA in situ hybridization, microarray development, or studies of protein synthesis machinery.

Features and Benefits

  • Minimizes risk of nuclease, protease, pyrogen or bacteria contamination.
  • Eliminates the need for toxic agents such as DEPC, therefore improving safety, saving time and reducing costs.
  • Bottom-tip is redesigned for a secured installation of the protection bell.
  • Easy maintenance: the polisher is easily installed and replaced; does not require sanitization.
  • e-Sure tag for RFID connection with POD enables full traceability (data management) and automatic consumable status monitoring on the POD′s touchscreen interface.

Other Notes

Directions For Use
Organism Retention: Bacteria and pyrogens
Mode of Action: Ultrafiltration
Application: Cell culture media, molecular biology
Intended Use: Bioburden reduction
Instructions for Use: This item provides water filtered through ultrafiltration hollow fibers. Refer to insert, section "replacement" in the product package.
Storage Statement: Store in dry location.
Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.
  • Pyrogens (endotoxins) < 0.001 EU/mL
  • RNases < 1 pg/mL
  • DNases < 5 pg/mL
  • Protease < 0.15 μg/mL
  • Bacteria < 0.01 CFU/mL

Legal Information

BIOPAK is a registered trademark of Merck KGaA, Darmstadt, Germany
Milli-Q is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Detection and Quantification of MicroRNAs by Ligase-Assisted Sandwich Hybridization on a Microarray
Iizuka R, et al.
Microarrays, 1368 (2016)
Graphene oxide size and oxidation degree govern its supramolecular interactions with siRNA
Reina G, et al.
Nanoscale, 10(30), 5965-5974 (2018)
Giacomo Reina et al.
Nanoscale, 10(13), 5965-5974 (2018-03-16)
Several studies have demonstrated the ability of graphene oxide (GO) to efficiently adsorb small-interfering RNA (siRNA) on its surface and to transport it into cells. However, studies on whether and how siRNA interacts with GO are still inconclusive. In this
Real-time assay for testing components of protein synthesis
Rosenblum G, et al.
Nucleic Acids Research, 40(12), e88-e88 (2012)
Andrea Bleckmann et al.
Methods in molecular biology (Clifton, N.J.), 1669, 159-171 (2017-09-25)
A key element to understand developmental and reproductive processes like germline development, double fertilization, and embryogenesis is the study of cell-specific gene expression patterns which is best analyzed by RNA in situ hybridization. Different visualization techniques have been established to

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