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  • Characterisation of the selective binding of antibiotics vancomycin and teicoplanin by the VanS receptor regulating type A vancomycin resistance in the enterococci.

Characterisation of the selective binding of antibiotics vancomycin and teicoplanin by the VanS receptor regulating type A vancomycin resistance in the enterococci.

Biochimica et biophysica acta (2017-05-18)
C S Hughes, E Longo, M K Phillips-Jones, R Hussain
RESUMO

A-type resistance towards "last-line" glycopeptide antibiotic vancomycin in the leading hospital acquired infectious agent, the enterococci, is the most common in the UK. Resistance is regulated by the VanR

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N-Acetylmuramic acid, ≥98% (TLC)