Peptide dendrimer-conjugates of ketoprofen: Synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery.

Peptide dendrimer-conjugates of ketoprofen: Synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2017-03-13)

Aswathi R Hegde, Prarthana V Rewatkar, Jyothsna Manikkath, Karnaker Tupally, Harendra S Parekh, Srinivas Mutalik

RESUMO

The aim of this study was to evaluate skin delivery of ketoprofen when covalently tethered to mildly cationic (2

MATERIAIS

Número do produto

Marca

Descrição do produto

Sigma-Aldrich

Triisopropylsilane, 98%

Sigma-Aldrich

HBTU, ≥98.0% (T)

Sigma-Aldrich

Fmoc-Lys(Fmoc)-OH, ≥98.0% (HPLC)