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Highly selective C-H functionalization/halogenation of acetanilide.

Journal of the American Chemical Society (2006-06-08)
Xiaobing Wan, Zhongxun Ma, Bijie Li, Keya Zhang, Shaokui Cao, Shiwei Zhang, Zhangjie Shi
RESUMO

Highly regioselective C-H functionalization/halogenation of acetanilides to produce ortho-haloacetanilides was catalyzed by Pd(OAc)2 and Cu(OAc) 2 with CuX2 as the halogen source.